Best Upright Mouse In June 2025

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This guide comes with the top 10 Best Upright Mouse available on the market. Therefore, if you are looking for the Best Upright Mouse, you have everything you need here.

To help you in your search, we have completed this list of the Best Upright Mouse.

Top Rated Best Upright Mouse Of 2025

Rank	Product Name	Score
1	Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buy Now	9.7 Buy Now
2	J-Tech Digital Wired Ergonomic Vertical USB Mouse with Adjustable Sensitivity (600/1000/1600 DPI), Scroll Buy Now	9.5 Buy Now
3	iClever Vertical Mouse - Ergonomic Mouse Wireless 6 Buttons with Adjustable DPI 1000/1600/2000/2400 Buy Now	9.1 Buy Now
4	Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100 Buy Now	8.8 Buy Now
5	MOJO Bluetooth Vertical Mouse - Wireless Optical Ergonomic Mouse w/Adjustable Sensitivity Buy Now	8.6 Buy Now
6	J-Tech Digital Scroll Endurance Wireless Mouse Ergonomic Vertical USB Mouse with Adjustable Sensitivity Buy Now	8.3 Buy Now
7	Ergonomic Mouse, Vertical Wireless Mouse - LEKVEY Rechargeable 2.4GHz Optical Vertical Mice : Buy Now	8.1 Buy Now
8	Rechargeable Ergonomic Wireless Mouse, 2.4G USB Optical Vertical Mouse with 3 Adjustable DPI Buy Now	7.8 Buy Now
9	VicTsing Ergonomic Mouse, Upgraded Vertical Wireless Mouse 2.4G Optical Mouse-Reduce Wrist Pain, 6 Buy Now	7.5 Buy Now
10	Ergonomic Wireless Mouse, Acedada Rechargeable 2.4G USB Wireless Vertical Ergonomic Mouse, 800/1200 /1600 Buy Now	7.2 Buy Now

1. Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5

• 800 / 1200 / 1600 dpi resolution optical tracking technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
• Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
• Added next/previous buttons provide convenience when webpage browsing, the superior choice for internet surfers, gamers and people who work at length at the computer.
• Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. product dimensions: 120*62.8*74.8 mm, product weight: 3.4 oz.
• Package includes: 1 anker wireless vertical ergonomic optical mouse (2 aaa batteries not included), 1 2.4g usb receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.

2. J-Tech Digital Wired Ergonomic Vertical USB Mouse with Adjustable Sensitivity (600/1000/1600 DPI),

• wide compatibility & free lifetime support compatible with windows 7/8/10, xp, vista 7/8 and linux etc. all j-tech digital products include a one-year manufacturer warranty and free lifetime technical support from our customer support team located in houston, texas - available m-f 9am-6pm cst - contact information available on the j-tech digital seller page.
• adjustable dpi switch between dpi levels 800, 1200 and 1600 to adjust mouse responsiveness depending on your need and/or preference. optical tracking technology ensures greater sensitivity for precise tracking on a wide range of surfaces.
• ergonomic design designed to be utilized in neutral "handshake" wrist and arm positions for smoother movement and less overall strain helping alleviate wrist pain.
• thumb buttons use the back/forward buttons located near the thumb area for optimum convenience, (button functionality can also be changed and reassigned using a compatible driver or software).
• removable palm rest & blue led trim this mouse comes included with a palm rest that can be easily detached based on the user's preference and convenience. it also features a blue led, which lights up the outlining of the mouse.

3. iClever Vertical Mouse - Ergonomic Mouse Wireless 6 Buttons with Adjustable DPI 1000/1600/2000/2400

• High-precision mouse control -- if you're someone who likes having exact control over your mouse movements, you've just found your new best friend. outfitted with an optical sensor of 2400 dpi, this ergonomic mouse tracks the finest of movements effortlessly. it carefully calculates weight, stability and control on almost any surface and can be adjusted between 4 resolu...
• Work anywhere with wireless -- the last thing you need is yet another cord to get tangled in. simply insert the usb receiver into your computer and you'e on your way. this wireless vertical mouse tracks every movement with its super-fast 2.4 ghz wireless connection, and never worry about delays or dropouts! thanks to the wireless range of 49 feet, you can enjoy a clutte...
• Whisper quiet click -- hours of clicking sounds can be annoying to you or those around you. the advanced stability built into the wireless ergonomic mouse reduces the tip noise and improves responsiveness so you can make each click precise and inaudible. we beat the competition, offering not only the quiet left and the right click buttons, but also the soundless scroll ...
• Easier web browsing -- get things done quicker with the wireless mouse, forget clicking the back button every time. with the built-in next/previous page buttons, you won't even have to move your wrist, simply click once and you'll jump to the desired page. long browsing sessions can wear down your hand, but thankfully this ergonomic wireless mouse reduces pressure on yo...
• Ergonomic design for ultimate comfort -- hours at the computer can leave your hand aching and result in carpal tunnel syndrome. give yourself the gift of comfort and style with this thoughtfully designed ergonomic vertical mouse! created with power-users in mind, the precision shaping is meant to relieve your wrist of pains and cramping, and features side grips, a thumb...

4. Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100

• Added next/previous buttons provide convenience when webpage browsing, the superior choice for internet surfers, gamers and people who work at length at the computer.
• Package includes: 1 anker vertical ergonomic optical mouse (with 4.9 ft cable), 1 instruction manual. includes 18 month warranty and lifetime technical support guarantee.
• 1.5m/4.9ft usb cable length, product dimensions: 120*62.8*74.8 mm, product weight: 5.3 oz.
• 1000/1600 dpi resolution optical tracking technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
• Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.

5. MOJO Bluetooth Vertical Mouse - Wireless Optical Ergonomic Mouse w/Adjustable Sensitivity

• Number of buttons: 6 (plus scroll wheel), all silent, powered by 1xaa batteries (included): adjustable dpi/sensitivity button, mode/pairing button, low battery indicator, next/last page (for web browsing)
• Dimensions: 5.4" (l) x 2.9" (w) x 2.7" (h), weight: 3.4 oz
• Dual mode - bluetooth or 2.4 ghz wireless mode (with dongle) - control two computers with one mouse
• Compatible with windows, mac, android, ios, linux (to use this mouse with an iphone or ipad you must update to ios 13 or above)
• "perfect grip" designed to reduce stress and discomfort associated with overuse in your hands, wrist, elbows, forearms, and shoulders by maintaining a neutral "handshake" grip.

6. J-Tech Digital Scroll Endurance Wireless Mouse Ergonomic Vertical USB Mouse with Adjustable

• Driver free 3-mode dpi shift:600/1000/1600dpi adjustable
• Receiver distance:10 meters nano receiver, the receiver is attached to the bottom of mouse.
• High-resolution optical sensor with adjustable sensitivity for accuracy and responsiveness
• Unique ergonomic design with removable palm rest to reduce hand and wrist pain
• Two thumb buttons can be used for back/forward browser navigation

7. Ergonomic Mouse, Vertical Wireless Mouse - LEKVEY Rechargeable 2.4GHz Optical Vertical Mice :

• Widely compatible -- widely compatible with windows 2000 / xp / vista / 7 / 8 / 10 / linux. note: not compatible with mac os, apple products once you get used to the ergonomic mouse, you will love it so much !
• High-capacity rechargeable battery -- built-in rechargeable battery. you no longer need to buy batteries, very convenient !! easy to use -- one nano usb receiver at the bottom of mouse, just plug and play!
• Ergonomic, sleek and rechargeable design -- scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain
• Great customer service -- rest assured that all our 7lucky ergonomic vertical mouse have unconditional 18-month product warranty ( replace or refund ) as well as lifetime easy-to-reach technical support
• Multifunction and convenient -- advanced "page back" and "page forward" functionality buttons provide convenience when web page browsing. 800 /1200/1600 dpi levels -- easily adjusts the sensitivity of the mouse

8. Rechargeable Ergonomic Wireless Mouse, 2.4G USB Optical Vertical Mouse with 3 Adjustable DPI

• High compatibility: compatible with windows/xp/mac os/vista/linux based operating systems. instantly connect to your macbook, imac, desktop, laptop, pc or other device. one nano usb receiver at the bottom of wireless mouse.
• Rechargeable ergonomic mouse: built-in rechargeable battery,no longer need to buy batteries.intelligent power saving in auto sleep mode after 8 minutes idle and awake the ergonomic vertical mouse by pressing right and left button.
• High sensitive control: has 6 buttons and 3 levels dpi to change among 800/1200/1600 -easily adjusts the sensitivity of the vertical computer mouse.reliable 2.4ghz wireless connection with high anti-interference performance within 10 meters.
• Ergonomic design mice: wireless vertical mice with 54 vertical angle helps to reduce wrist muscles strain,keep your wrist in a natural state, supports your right hand for comfortable control all day long. excellent cool wireless mice for computer/laptop working and surfing.
• Customer service: all our wireless ergonomic computer mice have 1 year quality guarantee,support replace or refund within warranty as well as lifetime technical support. any questions in using, please contact us as soon as possible.

9. VicTsing Ergonomic Mouse, Upgraded Vertical Wireless Mouse 2.4G Optical Mouse-Reduce Wrist Pain, 6

• 4 different sensitivity optionsthe victsing ergonomic wireless mouse has 4 adjustable dpi options (1000/1600/2000/2400 dpi), so you can easily change the cursor speed and enjoy different scenes. high dpi can improve your ergonomic wireless mouse accuracy. the highest dpi for this vertical wireles mouse is 2400, so that you can complete your tasks efficiently with effo...
• Designed for long-time usethis ergonomic wireless mouse has more buttons than a traditional mouse. not only can help you adjust your ergonomic vertical mouse's dpi freely, but the two buttons on the side also allow you to browse the web pages and documents faster. the victsing ergonomic wireless mouse uses skin-friendly materials, smooth to touch.this ergonomic mouse'...
• Easy of useadopted advanced 2.4ghz wireless technology can work stably and fast within 19.22ft/15m on your windows 10, windows vista, linux, mac os x, windows xp devices. this ergonomic mouse supports plug & play. you don't need to download any drivers or software, just plug the usb plug into your computer port and you can use the vertical mouse immediately. in additi...
• Ergonomic wireless mousevictsing ergonomic mouse dedicate to improving and alleviating hand fatigue. victsing ergonomic mouse use the exclusive 54 vertical angle encourages a healthy wrist and forearm posture which reduces muscle strain, so that your wrist and forearm smoother movement and less overall strain. the victsing vertical mouse is designed for dailywork and...
• Smart power saving mode this smart vertical mouse will automatically enter into sleeping mode(power-saving mode) after 10 minutes inactivity. press any button to wake the ergonomic wireless mouse up at any time. the vertical mouse's battery has a long lifetime. an independent switch button on the back helps save energy effectively and smartly. notice : backed by vic...

10. Ergonomic Wireless Mouse, Acedada Rechargeable 2.4G USB Wireless Vertical Ergonomic Mouse, 800/1200

• Scientific ergonomic design: the ergonomic design offers your hand maximum support for lasting comfort, encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
• Rechargeable wireless mouse: built-in high capacity rechargeable battery, no longer needs to buy batteries. easy to charge through micro usb charging cable (approx. 2-hour full). auto sleep mode and awake the wireless mouse by pressing any key. supports continue to use while charging so you dont have to worry about running out of power.
• Stable connection with less noise click: deliver a powerful, reliable 2.4ghz wireless mouse connection with high anti-interference performance with 32.8ft/10m transmission distance. quieter click makes you concentrate on the work without disturbing others beside you. just plug and play!one nano usb receiver at the bottom of mouse
• 6 buttons and 3 adjustable dpi: added next/previous functionality buttons provide convenience when web page browsing, the superior choice for internet surfers, players and people who work at length at the computer. 800 / 1200 / 1600 dpi resolution optical tracking technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide...
• Wide compatibility: well compatible with windows7/8/10/xp, vista7/8, and linux, etc. fits for desktop, laptop, pc, macbook and other devices.note: not compatible with mac os, apple products warranty -- this acedada wireless ergonomic mouse enjoys 2-year worry-free warranty as well as lifetime technical support.