Best Ortho Flea Spray In June 2025

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In this Best Ortho Flea Spray product guide, we’ll help you make a more informed decision and select the product with the benefits you need.

To help you in your search, we have completed this list of the Best Ortho Flea Spray.

Top Rated Best Ortho Flea Spray Of 2025

Rank	Product Name	Score
1	Ortho Home Defense Max Bed Bug, Flea and Tick Killer - With Ready-to-Use Buy Now	9.7 Buy Now
2	Ortho BugClear Insect Killer for Lawns & Landscapes Ready to Spray - Kills Buy Now	9.5 Buy Now
3	Ortho Home Defense Insect Killer for Lawn & Landscape Ready-to-Spray - Treats up Buy Now	9.1 Buy Now
4	Ortho Home Defense Insect Killer for Indoor & Perimeter2 - with Comfort Wand Buy Now	8.8 Buy Now
5	Ortho Home Defense Dual-Action Bed Bug Killer Aerosol, 18 oz Buy Now	8.6 Buy Now
6	Ortho Home Defense Insect Killer for Lawns Granules - Treats up to 10,000 Buy Now	8.3 Buy Now
7	Ortho Home Defense Max Indoor Insect Barrier - with Extended Reach Comfort Wand Buy Now	8.1 Buy Now
8	Ortho Home Defense Bed Bug Killer with Essential Oils, 14 oz Buy Now	7.8 Buy Now
9	Ortho Bed Bug & Flea Killer Aerosol, 16 oz Buy Now	7.5 Buy Now
10	Proof Bed Bug & Dust Mite Killer (Spray, Large) Buy Now	7.2 Buy Now

1. Ortho Home Defense Max Bed Bug, Flea and Tick Killer - With Ready-to-Use

• Kills even the toughest bed bugs (pyrethroid-resistant bed bugs)
• The continuous spray comfort wand easily gets into hard-to-reach areas
• Use ortho home defense max bed bug, flea & tick killer to kill bed bugs, bed bug eggs, fleas, and ticks
• Use spray as a spot treatment around bed frames, mattress seams/tufts/folds, and baseboards
• Second step of a 3-step bed bug solution system

2. Ortho BugClear Insect Killer for Lawns & Landscapes Ready to Spray - Kills

• Easily apply insect spray by connecting a garden hose to the attached sprayer
• Kill 235 bugs, including ants, ticks, mosquitoes, fleas & spiders, with ortho bugclear insect killer for lawns & landscapes ready-to-spray
• Use on lawns, around a home's perimeter, and on ornamentals, flowers, trees, shrubs, vegetables & fruit trees
• Provides treatment for a 5,300 sq. ft. lawn, 1,400 sq. ft. of foundation/perimeter, or across 2,700 sq. ft. of foliage
• Starts killing within minutes and provides long-lasting control

3. Ortho Home Defense Insect Killer for Lawn & Landscape Ready-to-Spray - Treats up

• Kill outdoor insects: starts working within minutes to kill listed outdoor bugs, so those lawn insects won't come inside your home
• Ortho home defense insect killer for lawn & landscape ready-to-spray kills 235 listed insects, including ants, ticks, mosquitoes, fleas & spiders outside before they come inside, plus it even creates a bug barrier to keep them out
• Keep bugs out: create a barrier that keeps insects from coming inside your house (see product label for complete lists of pests)
• Easy to apply: one bottle treats up to 5,300 sq. ft., and there's no mixing or measuring--just attach to your garden hose and spray, people and pets may re-enter after the treated area has been allowed to dry
• Long-lasting control: this insect spray keeps on killing ants, spiders (excluding black widow), and american dog ticks for an impressive 3 months

4. Ortho Home Defense Insect Killer for Indoor & Perimeter2 - with Comfort Wand

• Keeps bugs outside: creates a bug barrier that will kill bugs you have and prevents new bugs for up to 12 months (applies to ants, roaches and spiders indoors on non-porous surfaces)
• Ortho home defense insect killer for indoor & perimeter2 with comfort wand kills ants, cockroaches, spiders, fleas, ticks and other listed bugs, the formula is odor free, won't stain, and keeps listed bugs out
• Wand makes application easy: the comfort wand eliminates hand fatigue, and there's no pumping required, making it easy to spray along your home's perimeter--indoors and outside
• Kills bugs inside: kills those annoying home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, beetles, silverfish, centipedes and millipedes
• No staining or stink: this spray can be used indoors and out, leaves no residue, and has no odor, people and pets may re-enter treated areas after spray has dried

5. Ortho Home Defense Dual-Action Bed Bug Killer Aerosol, 18 oz

• Kills bed bug eggs
• Use on beds, furniture and luggage
• Kills parathyroid-resistant bed bugs
• Long-lasting bed bug control
• Fast-acting formula
• Kills bed bugs, fleas and brown dog ticks

6. Ortho Home Defense Insect Killer for Lawns Granules - Treats up to 10,000

• Easy to apply: one 10 lb. bag treats up to 10,000 square feet--for best results, apply with a scotts spreader and water in immediately after application, people and pets may re-enter after the treated area has dried
• Outdoor protection: protect your home with this outdoor flea and tick killer, for best results, apply proactively in the early spring or summer to prevent infestation
• Ortho home defense insect killer for lawns granules is an outdoor insect killer that kills ants, ticks, fleas, spiders and centipedes in your lawn before they can come inside your home, and creates a bug barrier to keep them out
• Long-lasting control: kill outdoor pests before they come into your home for up to 3 months, including listed ants, ticks, and spiders (see product label for complete lists of pests)
• Fast acting: starts creating a bug barrier within minutes to kill listed outdoor bugs in your lawn, on ornamentals and flowers, and around your home's foundation

7. Ortho Home Defense Max Indoor Insect Barrier - with Extended Reach Comfort Wand

• Start killing ants, roaches, spiders, fleas and ticks fast with ortho home defense max indoor insect barrier
• The extended reach comfort wand lets you spray without bending
• Dries fast and reaches insects where they hide
• Kills and protects for 365 days against ants, roaches and spiders indoors on nonporous surfaces
• Use indoors with confidence wherever insects are--in kitchens, bathrooms, and basements, and around doors and windows

8. Ortho Home Defense Bed Bug Killer with Essential Oils, 14 oz

• Safe to use around kids and pets (when used as directed)
• Even kills resistant bed bugs - 100% satisfaction guaranteed (see product label for details)
• And strong essential oil formula (safe to use around kids and pets when used as directed)
• Spray at all angles
• Tested and proven to start killing bed bugs in seconds

9. Ortho Bed Bug & Flea Killer Aerosol, 16 oz

• Apply at the first sign of bed bug activity
• Also kills fleas, ticks, dust mites and lice
• Kills bed bugs and their eggs
• Non-staining on water safe fabrics and surfaces
• Can be used indoors on carpet, mattresses, box springs, furniture, bedding, floors, rugs, garments and luggage.

10. Proof Bed Bug & Dust Mite Killer (Spray, Large)

• It works, guaranteed - you are protected by our iron-clad, 100% satisfaction guaranteed. if, for any reason, you are not fully satisfied with proof bed bug spray, simply return it for a full refund. it will work for you, guaranteed!
• Extremely effective! - can be used safely on your mattresses, curtains, carpets, furniture, and more.
• Kill 100% bed bugs in your home - our most advanced formula - targets and attacks bed bug and dust mite micropores uses an advanced non-toxic mode of action.
• Powerful plant-based ingredients - results with lab tested organic neem oil.
• Lab tested - keeps killing adults for up to 2 weeks and eggs for up to 3 weeks when used as directed. 100% effective at killing bed bugs and their nests.