Best Antihistamine For Children In April 2025

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If you are looking for the Best Antihistamine For Children of top quality, read our detailed reviews on them here before making the purchase decision.

To help you in your search, we have completed this list of the Best Antihistamine For Children.

Top Rated Best Antihistamine For Children Of 2025

Rank Product Name Score
1
Allegra Children's Non-Drowsy Antihistamine Liquid for 12-Hour Allergy Relief, 30 mg 4 oz
Allegra Children's Non-Drowsy Antihistamine Liquid for 12-Hour Allergy Relief, 30 mg 4 oz
9.7
2
Claritin Children's 24 Hour Allergy Medicine for Kids, Non-Drowsy Allergy Relief, Loratadine Antihistamine
Claritin Children's 24 Hour Allergy Medicine for Kids, Non-Drowsy Allergy Relief, Loratadine Antihistamine
9.5
3
ValuMeds Allergy Medicine (600 Tablets) Antihistamine, Diphenhydramine HCl 25 mg | Children
ValuMeds Allergy Medicine (600 Tablets) Antihistamine, Diphenhydramine HCl 25 mg | Children
9.1
4
Alaway Antihistamine Eye Drops, 0.34 fl oz (10 ml)
Alaway Antihistamine Eye Drops, 0.34 fl oz (10 ml)
8.8
5
Benadryl Ultratabs Antihistamine Allergy Relief Tablets, Diphenhydramine HCl 25mg, 100 ct
Benadryl Ultratabs Antihistamine Allergy Relief Tablets, Diphenhydramine HCl 25mg, 100 ct
8.6
6
Basic Care Children’s All Day Allergy, Cetirizine Hydrochloride Oral Solution 1 mg/mL, Grape
Basic Care Children’s All Day Allergy, Cetirizine Hydrochloride Oral Solution 1 mg/mL, Grape
8.3
7
Allegra Children's Allergy 12 Hour Orally Disintegrating Tablets Orange Cream Flavor, 24 Tablets
Allegra Children's Allergy 12 Hour Orally Disintegrating Tablets Orange Cream Flavor, 24 Tablets
8.1
8
Children's Zyrtec 24 HR Dissolving Allergy Relief Tablets with Cetirizine, Citrus Flavored, 24
Children's Zyrtec 24 HR Dissolving Allergy Relief Tablets with Cetirizine, Citrus Flavored, 24
7.8
9
Children's Claritin 24 Hour Non-Drowsy Allergy Grape Chewable Tablet, 5mg, 30Ct
Children's Claritin 24 Hour Non-Drowsy Allergy Grape Chewable Tablet, 5mg, 30Ct
7.5
10
Kids Allergy Medicine by Hyland's 4Kids, Non Drowsy Childrens Complete Allergy Relief Syrup
Kids Allergy Medicine by Hyland's 4Kids, Non Drowsy Childrens Complete Allergy Relief Syrup
7.2

1. Allegra Children's Non-Drowsy Antihistamine Liquid for 12-Hour Allergy Relief, 30 mg 4 oz

1
9.7/10 our score

  • Non-drowsy: formulated with active ingredient fexofenadine, a non-drowsy antihistamine
  • Berry flavor liquid: this allergy medicine for children 2 years and older comes in a berry flavor and goes down smooth
  • 12-hour relief: one dose of children's allegra provides 12 hours of powerful relief from their worst allergy symptoms
  • Includes: one 4-ounce bottle of allegra children's non-drowsy antihistamine liquid for 12-hour allergy relief
  • Indoor & outdoor allergies: use allegra tablets for indoor and outdoor allergies, including seasonal allergies and pet allergies

2. Claritin Children's 24 Hour Allergy Medicine for Kids, Non-Drowsy Allergy Relief, Loratadine

2
9.5/10 our score

  • For children ages 2+, 24-hour allergy relief of runny nose, sneezing, itchy, watery eyes and itchy nose or throat
  • Claritin children's grape syrup is a non-drowsy oral solution, loratadine 5mg per 5ml
  • Children's claritin is the number 1 pediatrician recommended non-drowsy oral allergy medicine brand
  • Dye-free, sugar-free, alcohol-free, kosher certified
  • Claritin is an antihistamine so it hinders the cascade triggered by allergens
  • Allergy relief for symptoms triggered by over 200 different allergens from pets, pollen, dust and mold

3. ValuMeds Allergy Medicine (600 Tablets) Antihistamine, Diphenhydramine HCl 25 mg | Children

3
9.1/10 our score

  • Clear, healthy eyes reduce the dry, itchy eyes and redness caused by pollen, dander, and seasonal allergies for true clarity.
  • Relieve common cold symptoms this anti-allergy medicine for kids and adults also helps reduce sneezing and itchy noses and throats.
  • Use as directed these hcl antihistamine tablets should always be used as directed. please read package for more details on proper use and dosage.
  • Rest better diphenhydramine hcl can cause drowsiness which can help your body relax for a better nights rest. avoid driving after use.
  • Breathe a little easier a powerful antihistamine, our formula helps control coughs and runny noses for clearer, healthier breathing.

4. Alaway Antihistamine Eye Drops, 0.34 fl oz (10 ml)

4
8.8/10 our score

  • Single 0.34 ounce bottle
  • Original prescription strength
  • Up to 12 hours relief
  • Itch relief within minutes

5. Benadryl Ultratabs Antihistamine Allergy Relief Tablets, Diphenhydramine HCl 25mg, 100 ct

5
8.6/10 our score

  • Allergy medicine tablets for multi-symptom allergy relief intended to be used by adults and children ages six and up for relief of both indoor and outdoor allergies
  • Active ingredient, diphenhydramine hcl, provides relief for hay fever or other upper respiratory allergy symptoms and cold symptoms like sneezing and runny nose
  • Works when you need it most with an allergy medicine in small, convenient antihistamine tablets that put your allergies to rest
  • 100-count pack of benadryl ultratabs antihistamine allergy relief tablets each containing 25 mg of the antihistamine diphenhydramine hcl for allergy relief that works when you need it most
  • Provides allergy medicine for sneezing, runny nose, itchy nose or throat, and itchy, watery eyes and cold symptoms like sneezing and runny nose

6. Basic Care Children’s All Day Allergy, Cetirizine Hydrochloride Oral Solution 1 mg/mL, Grape

6
8.3/10 our score

  • 24 hour allergy relief: this children's allergy medicine provides 24 hours of relief from runny nose, sneezing, itchy nose or throat and itchy, watery eyes.
  • Children's allergy medicine: provides indoor and outdoor allergy relief in a grape flavored cetirizine hydrochloride oral solution kids will love.
  • Allergy causes: when you're exposed to the same allergen twice, your antibodies can release a number of immune system chemicals, such as histamine, that cause allergy symptoms. basic care children's all day allergy contains cetirizine hydrochloride 5 mg/5 ml, an antihistamine which can help.
  • Indoor & outdoor allergy relief: temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose, sneezing, itching of the nose or throat and itchy, watery eyes.
  • Active ingredient: basic care children's all-day allergy contains cetirizine hydrochloride 5 mg/5 ml, an antihistamine, which compares to the active ingredient in children's zyrtec.

7. Allegra Children's Allergy 12 Hour Orally Disintegrating Tablets Orange Cream Flavor, 24 Tablets

7
8.1/10 our score

  • Melting tablets: children's allegra tablets melt on their tongue without water and come in a orange cream flavor
  • Non-drowsy: formulated with active ingredient fexofenadine, a non-drowsy antihistamine
  • Indoor & outdoor allergies: use allegra tablets for indoor and outdoor allergies, including seasonal allergies and pet allergies
  • Includes: one 24-count pack of allegra children's non-drowsy antihistamine tablets for 12-hour allergy relief
  • 12-hour relief: one dose of children's allegra provides 12 hours of powerful relief from their worst allergy symptoms

8. Children's Zyrtec 24 HR Dissolving Allergy Relief Tablets with Cetirizine, Citrus Flavored, 24

8
7.8/10 our score

  • Give your child effective relief from hay fever and other upper respiratory allergies with this prescription-strength allergy medicine for kids
  • Zyrtec children's dissolving tablets work for a full 24 hours, providing consistently powerful relief of your child's allergies
  • Intended for children ages 6 and older, zyrtec kids' allergy tablets can be taken with or without water to help relieve symptoms of both indoor and outdoor allergies
  • 24-count bottle of children's zyrtec 24 hour allergy dissolve tablets for all-day relief of allergy symptoms including runny nose, sneezing, itchy, watery eyes, and itchy nose & throat.
  • Each allergy tablet contains 10 milligrams of effective cetirizine hydrochloride antihistamine and melts in the mouth with a kid-friendly citrus flavor

9. Children's Claritin 24 Hour Non-Drowsy Allergy Grape Chewable Tablet, 5mg, 30Ct

9
7.5/10 our score

  • Provides 24-hour allergy relief of runny nose, sneezing, itchy, watery eyes and itchy nose or throat
  • Grape flavor
  • 24-hour, non-drowsy indoor and outdoor allergy relief
  • Children's claritin is the #1 pediatrician recommended non-drowsy oral allergy brand.*
  • Kid approved great taste

10. Kids Allergy Medicine by Hyland's 4Kids, Non Drowsy Childrens Complete Allergy Relief Syrup

10
7.2/10 our score

  • Relief of sneezing, runny nose, itchy and watery eyes: natural relief of symptoms of indoor and outdoor allergens including itchy nose and throat, itchy, watery eyes, runny nose and sneezing in children ages 2-12
  • Safe and non-habit forming: our gentle homeopathic formulas are made with all natural active ingredients. there are no known side-effects and will not conflict with any medications you may be taking
  • Easy to take: natural syrup to relieve itchy nose & throat, itchy, watery eyes, runny nose and sneezing
  • 4 ounces= 24 doses of hyland's 4 kids complete allergy relief syrup

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