Best Cold And Flu Medicine For Adults Non Drowsy In May 2025

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If you are ready to choose a new Best Cold And Flu Medicine For Adults Non Drowsy, check out our detailed recommendation below!.

To help you in your search, we have completed this list of the Best Cold And Flu Medicine For Adults Non Drowsy.

Top Rated Best Cold And Flu Medicine For Adults Non Drowsy Of 2025

Rank	Product Name	Score
1	Tylenol Sinus + Headache Non-Drowsy Daytime Caplets with Acetaminophen & Phenylephrine HCl, 24 Buy Now	9.7 Buy Now
2	Boiron Coldcalm, 60 Tablets, Homeopathic Medicine for Cold Relief Buy Now	9.5 Buy Now
3	Vicks DayQuil Cold and Flu Multi-Symptom Relief, 48 LiquiCaps (Non-Drowsy) - Sore Throat Buy Now	9.1 Buy Now
4	Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count Buy Now	8.8 Buy Now
5	Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 36 ct Buy Now	8.6 Buy Now
6	Vicks DayQuil and NyQuil SEVERE Cough, Cold and Flu Relief, 48 LiquiCaps Buy Now	8.3 Buy Now
7	Coricidin HBP Decongestant-Free Cough and Cold Medicine for Hypertensives, Cold Symptom Relief Buy Now	8.1 Buy Now
8	Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Powermax Liquid Gels Buy Now	7.8 Buy Now
9	Nature's Way Umcka Cold+Flu Multi-Action Non-Drowsy Relief, Fructose-Free Syrup, 99.95% Alcohol Free, Berry Buy Now	7.5 Buy Now
10	Medique Products 82233 Cold Relief Tablets, 100 Tablets Buy Now	7.2 Buy Now

1. Tylenol Sinus + Headache Non-Drowsy Daytime Caplets with Acetaminophen & Phenylephrine HCl, 24

• Pain reliever and decongestant formulated to temporarily relieve symptoms of nasal congestion, sinus headache and pressure
• From the #1 doctor-recommended pain relief brand, these sinus relief caplets are suitable for adults and children ages 12 years and older
• 24-count box of tylenol sinus + headache daytime caplets for non-drowsy sinus symptom relief due to the common cold, hay fever or other respiratory allergies
• Each caplet contains 325 mg of acetaminophen to temporarily relieve pain and reduce fever as well as 5 mg of phenylephrine hcl, a nasal decongestant to help clear nasal passages
• The non-drowsy formula of this sinus medicine provides effective daytime symptom relief by promoting sinus drainage and helping to decongest sinus openings and passages

2. Boiron Coldcalm, 60 Tablets, Homeopathic Medicine for Cold Relief

• At boiron, we believe theres more than one way to feel better. since 1932, the boiron family has been committed to providing quality medicines. as world leader in homeopathy, our passion is your health. our promise is your satisfaction.
• Boiron cough, cold and flu medicines do not cause drowsiness or sleeplessness
• Coldcalm tablets address symptoms at every stage of a cold. it temporarily relieves symptoms such as sneezing, runny nose, nasal congestion and minor sore throat.
• Recommended for everyone ages 3 and up, andis available in a box of 60 quick-dissolving tablets.
• Coldcalm tablets do not cause drowsiness and it has no known interactions with other medications.

3. Vicks DayQuil Cold and Flu Multi-Symptom Relief, 48 LiquiCaps (Non-Drowsy) - Sore Throat

• Non-drowsy, daytime relief. dayquil cold & flu liquicaps help you get your power back so you can enjoy the day
• Active ingredients: acetaminophen 325mg, dextromethorphan hbr 10mg, phenylephrine hcl 5mg, do not refrigerate
• #1 pharmacist recommended over-the-counter cold & cough medicine from vicks, the worlds #1 selling cough & cold brand
• Multi-symptom relief. dayquil cold & flu contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
• Powerful 6-symptom relief. temporarily relieves common cold & flu symptoms, including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches & pains, and fever
• Non-drowsy.

4. Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count

• Cold and flu symptoms: influenza (flu) and the common cold are respiratory illnesses caused by viruses. the cold has a gradual onset of symptoms, such as cough, sore throat and runny or stuffy nose. the flu has a sudden onset of symptoms, such as a fever over 100.4f, headache, nasal congestion, sore throat, fatigue and weakness, chills and sweats, and aching muscles, e...
• Non-drowsy daytime cold and flu medicine provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains.
• Active ingredients: daytime cold & flu relief contains acetaminophen (pain reliever/fever reducer), dextromethorphan hbr (cough suppressant) and phenylephrine hcl (nasal decongestant) which compares to the active ingredients in vicks dayquil cold & flu. nighttime cold & flu relief contains acetaminophen (pain reliever/fever reducer), dextromethorphan hbr (cough suppre...
• Nighttime cold and flu medicine provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains.
• Pain reliever and fever reducer: both daytime and nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat.

5. Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 36 ct

• 36-count of sudafed pe sinus congestion maximum strength non-drowsy tablets for fast, powerful relief of sinus pressure and sinus and nasal congestion
• Each coated tablet contains 10 milligrams of phenylephrine hcl, a nasal decongestant that provides non-drowsy symptom relief
• From the #1 pharmacist recommended brand among oral otc decongestants, this non-drowsy decongestant can be used by adults and children 12 years and older for fast, powerful relief
• This sinus congestion & pressure relief medicine also helps reduce nasal swelling to help you breathe easier, and can be taken every 4 hours as necessary for effective relief of cold and allergy symptoms
• The maximum strength formula helps clear sinus congestion and relieve sinus pressure due to the common cold, hay fever or other upper respiratory allergies

6. Vicks DayQuil and NyQuil SEVERE Cough, Cold and Flu Relief, 48 LiquiCaps

• Pain relief & fever reducer. dayquil/nyquil severe is an over-the-counter medicine that contains acetaminophen, a pain reliever and fever reducer that can help soothe sore throat
• Our smallest most powerful nighttime liquicap. nyquil severe relieves your sneezing, sore throat, headache, minor aches & pains, fever, runny nose, and cough, so you can get the rest you need
• Smallest branded, 4-active, maximum strength daytime liquicaps. dayquil severe offers non-drowsy relief of your cold and flu symptoms, so you can power through your day
• Maximum strength cold & flu relief. dayquil/nyquil severe delivers maximum symptom-fighting ingredients to relieve your worst cold & flu symptoms, such as cough, sore throat, fever, and congestion, day or night
• Multi-symptom relief with nyquil severe cold & flu, which also contains a nasal decongestant and dayquil severe cold & flu, which contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive

7. Coricidin HBP Decongestant-Free Cough and Cold Medicine for Hypertensives, Cold Symptom Relief

• The #1 brand that gives powerful cold symptom relief without raising your blood pressure
• Decongestant-free cold relief for people with high blood pressure
• Bayer consumer care
• Provides fast, powerful cold relief for people with high blood pressure
• Decongestant free
• Relieves cough, runny nose, and sneezing

8. Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Powermax Liquid Gels

• Fast relief so you can get back to your busy life. use as directed.
• Maximum strength day time and night time relief from your worst cold & flu symptoms
• 25% smaller pill: alka-seltzer plus maximum strength cold & flu powermax gels have a concentrated formula to provide powerful fast relief
• Covered by bayer healthcare llc-consumer health 60-day satisfaction guarantee.
• Day time multi-symptom relief of nasal congestion, cough, headache, body ache, sore throat, sinus pressure and fever. night time multi-symptom relief of runny nose, nasal congestion, cough, headache, body ache, sore throat and fever.

9. Nature's Way Umcka Cold+Flu Multi-Action Non-Drowsy Relief, Fructose-Free Syrup, 99.95% Alcohol

• Shortens duration and reduces severity: cough,congestion,hoarseness, sore throat, sneezing and stuffy/runny nose
• Great tasting: berry flavored. quickly absorbed soothing syrup. non- drowsy, suitable for children
• Traditional roots: umcka is made from pelargonium sidoides roots and originates from traditional south african medicine
• Clinically proven: umcka (pelargonium sidoides 1x) is proven effective in clinical studies for alleviating common colds plus nasal, throat and bronchial irritations
• Works differently: umcka does more than just relieve common cold and cough symptoms - it actually speeds your recovery time

10. Medique Products 82233 Cold Relief Tablets, 100 Tablets

• Individual tamper evident packets
• Each box contains 50 packets, 2 pills per packet
• Each tablet contains acetaminophen 325mg, guaifenesin 200mg, phenylephrine hci 5mg and dextromethorphan habra 15mg
• Non-drowsy, fast-acting, multi-symptom formula
• Easy dispensing box