Best Cold Medication For Adults In May 2025

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In this article, we will present the top 10 Best Cold Medication For Adults available on the market, along with our expert reviews. Get one of them and have fun! You’ll love it!

To help you in your search, we have completed this list of the Best Cold Medication For Adults.

Top Rated Best Cold Medication For Adults Of 2025

Rank	Product Name	Score
1	Vicks DayQuil Cold and Flu Multi-Symptom Relief, 48 LiquiCaps (Non-Drowsy) - Sore Throat Buy Now	9.7 Buy Now
2	Vicks DayQuil and NyQuil SEVERE Cough, Cold and Flu Relief, 48 LiquiCaps Buy Now	9.5 Buy Now
3	Cold Cough & Flu, Mucinex Fast-Max Day Time Severe Cold & Night Time Buy Now	9.1 Buy Now
4	Vicks Dayquil and Nyquil Cough, Cold and Flu Relief Combo, 72 LiquiCaps Buy Now	8.8 Buy Now
5	Theraflu MultiSymptom Severe Cold Relief Medicine/Nighttime Severe Cold & Cough Relief Medicine Powder Buy Now	8.6 Buy Now
6	Vicks NyQuil Cough, Cold & Flu Nighttime Relief, 48 LiquiCaps - #1 Pharmacist Buy Now	8.3 Buy Now
7	Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count Buy Now	8.1 Buy Now
8	ZICAM Cold Remedy Ultimate Orange Fruit Drops, Homeopathic Medicine for Shortening Colds, 25 Buy Now	7.8 Buy Now
9	Contac Cold + Flu, Maximum Strength Non-Drowsy Formula Caplets, 24 Count Buy Now	7.5 Buy Now

1. Vicks DayQuil Cold and Flu Multi-Symptom Relief, 48 LiquiCaps (Non-Drowsy) - Sore Throat

• Powerful 6-symptom relief. temporarily relieves common cold & flu symptoms, including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches & pains, and fever
• Active ingredients: acetaminophen 325mg, dextromethorphan hbr 10mg, phenylephrine hcl 5mg, do not refrigerate
• Multi-symptom relief. dayquil cold & flu contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
• Non-drowsy.
• Non-drowsy, daytime relief. dayquil cold & flu liquicaps help you get your power back so you can enjoy the day
• #1 pharmacist recommended over-the-counter cold & cough medicine from vicks, the worlds #1 selling cough & cold brand

2. Vicks DayQuil and NyQuil SEVERE Cough, Cold and Flu Relief, 48 LiquiCaps

• Maximum strength cold & flu relief. dayquil/nyquil severe delivers maximum symptom-fighting ingredients to relieve your worst cold & flu symptoms, such as cough, sore throat, fever, and congestion, day or night
• Pain relief & fever reducer. dayquil/nyquil severe is an over-the-counter medicine that contains acetaminophen, a pain reliever and fever reducer that can help soothe sore throat
• Our smallest most powerful nighttime liquicap. nyquil severe relieves your sneezing, sore throat, headache, minor aches & pains, fever, runny nose, and cough, so you can get the rest you need
• Multi-symptom relief with nyquil severe cold & flu, which also contains a nasal decongestant and dayquil severe cold & flu, which contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
• Smallest branded, 4-active, maximum strength daytime liquicaps. dayquil severe offers non-drowsy relief of your cold and flu symptoms, so you can power through your day

3. Cold Cough & Flu, Mucinex Fast-Max Day Time Severe Cold & Night Time

• Night time: relieves runny nose & sneezing
• Day & night: controls cough
• Day time: relieves nasal & chest congestion, thins & loosens mucus
• Day & night: relieves aches, fever, & sore throat
• 1 dose, 9 symptom relief, max strength day & night formula

4. Vicks Dayquil and Nyquil Cough, Cold and Flu Relief Combo, 72 LiquiCaps

• Dayquil non-drowsy, multi-symptom daytime relief. temporarily relieves common cold & flu symptoms, including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches & pains, and fever
• Powerful cold symptom relief, day or night. get powerful 6-symptom relief with dayquil/nyquil liquicaps
• #1 pharmacist recommended over-the-counter cold & cough medicine from vicks, the worlds #1 selling cough & cold brand
• Nyquil nighttime relief. temporarily relieves common cold & flu symptoms, including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing so you can sleep
• Multi-symptom relief with nyquil cold & flu, which also contains a nasal decongestant and dayquil cold & flu, which contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive

5. Theraflu MultiSymptom Severe Cold Relief Medicine/Nighttime Severe Cold & Cough Relief Medicine

• Cold, flu, & cough relief powder for adults and children 12 years of age and older
• Severe cold, flu & cough medicine, relieves symptoms such as: sore throat, headache, minor body aches & pains, nasal and sinus congestion
• Delicious green tea and honey lemon flavors in multisymptom severe cold and honey lemon, chamomile, and white tea flavors in nighttime severe cold & cough
• Non-drowsy multisymptom & nighttime cold & cough relief medicines for severe cold & flu symptoms
• Temporarily reduces fever associated with cold & flu symptoms

6. Vicks NyQuil Cough, Cold & Flu Nighttime Relief, 48 LiquiCaps - #1 Pharmacist

• Powerful nighttime releief. nyquil cold & flu liquicaps temporarily relieves common cold and flu symptoms, including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing
• #1 pharmacist recommended over-the-counter cold & cough medicine from vicks, the worlds #1 selling cough & cold brand
• Contains acetaminophen: a pain reliever/fever reducer than can help soothe your sore throat
• Multi-symptom relief. nyquil cold & flu contains a nasal decongestant for your toughest nasal congestion and sinus pressure
• Relieves your cold symptoms so you can sleep better. nyquil helps to relieve your cold & flu symptoms, so you can get the rest you need

7. Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count

• Nighttime cold and flu medicine provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains.
• Cold and flu symptoms: influenza (flu) and the common cold are respiratory illnesses caused by viruses. the cold has a gradual onset of symptoms, such as cough, sore throat and runny or stuffy nose. the flu has a sudden onset of symptoms, such as a fever over 100.4f, headache, nasal congestion, sore throat, fatigue and weakness, chills and sweats, and aching muscles, e...
• Non-drowsy daytime cold and flu medicine provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains.
• Active ingredients: daytime cold & flu relief contains acetaminophen (pain reliever/fever reducer), dextromethorphan hbr (cough suppressant) and phenylephrine hcl (nasal decongestant) which compares to the active ingredients in vicks dayquil cold & flu. nighttime cold & flu relief contains acetaminophen (pain reliever/fever reducer), dextromethorphan hbr (cough suppre...
• Pain reliever and fever reducer: both daytime and nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat.

8. ZICAM Cold Remedy Ultimate Orange Fruit Drops, Homeopathic Medicine for Shortening Colds, 25

• Zicam for shorter colds: zicam homeopathic cold remedy is meant to be used at the beginning of a cold. try zicam the next time you feel the first sniffle, sneeze or cough of an oncoming cold. satisfaction guaranteed.
• Zicam cold remedy fruit drops: packed with natural orange power, these homeopathic cold remedy gummy-like drops contain zinc and help shorten the length of colds when taken at the first sign.
• Zicam homeopathic remedies: known for zicam cold remedy products, we also offer products for homeopathic allergy relief, homeopathic cold relief for kids, & nasal congestion & sinus relief.
• From cold to no cold: zicam cold remedy products are clinically proven to shorten colds when taken at the first sign, so you feel better, faster. help calm your cold with zicam cold remedy products like nasal spray & swabs or our rapidmelt tablets.
• Cold remedy fruit drops: the only medicated fruit drop in orange flavor clinically proven to shorten colds when taken at the first sniffle, sneeze, or cough. getting better tastes better with zicam, the #1 pharmacist recommended brand.*

9. Contac Cold + Flu, Maximum Strength Non-Drowsy Formula Caplets, 24 Count

• 24 caplets per box.
• Symptom relief: contac cold + flu day caplets provide symptom relief for nasal congestion, sinus pressure, sore throat, head & minor body aches, and fever.
• Max strength: maximum strength, multi-symptom cold + flu relief
• Non-drowsy: contac cold + flu day provides multi-symptom relief in a non-drowsy caplet.
• Contac cold + flu: contains maximum strength active ingredients.