Best Cold Sore Medicine For Lips In April 2025

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If you are looking for the Best Cold Sore Medicine For Lips of top quality, read our detailed reviews on them here before making the purchase decision.

To help you in your search, we have completed this list of the Best Cold Sore Medicine For Lips.

Top Rated Best Cold Sore Medicine For Lips Of 2025

Rank Product Name Score
1
Orajel Touch-Free Cold Sore Patented Treatment .08 OZ
Orajel Touch-Free Cold Sore Patented Treatment .08 OZ
9.7
2
DocoShield Cold Sore Prevention Lip Balm w/Docosanol and Lysine (3-Pack)
DocoShield Cold Sore Prevention Lip Balm w/Docosanol and Lysine (3-Pack)
9.5
3
Abreva Docosanol 10% Cream Pump, Only FDA Approved Treatment for Cold Sore/Fever Blister
Abreva Docosanol 10% Cream Pump, Only FDA Approved Treatment for Cold Sore/Fever Blister
9.1
4
Abreva Docosanol Cold Sore Treatment 10% Cream Tube, Only FDA Approved Treatment
Abreva Docosanol Cold Sore Treatment 10% Cream Tube, Only FDA Approved Treatment
8.8
5
Abreva Cold Sore/Fever Blister Treatment, Pump 0.07 oz (2 g) (Abreva Pump)
Abreva Cold Sore/Fever Blister Treatment, Pump 0.07 oz (2 g) (Abreva Pump)
8.6
6
Lip Clear Lysine+ Cold Sore Treatment 0.25 oz
Lip Clear Lysine+ Cold Sore Treatment 0.25 oz
8.3
7
Abreva Cold Sore & Fever Blister Treatment, .07 oz
Abreva Cold Sore & Fever Blister Treatment, .07 oz
8.1
8
Cold Sores Begone Cold Sore Treatment 1 Stick 0.15 Ounce
Cold Sores Begone Cold Sore Treatment 1 Stick 0.15 Ounce
7.8
9
Herpecin L Lip Balm Stick, SPF 30 & Lysine, 0.1 Ounce Tube
Herpecin L Lip Balm Stick, SPF 30 & Lysine, 0.1 Ounce Tube
7.5
10
Abreva Cold Sore Treatment .07 Oz
Abreva Cold Sore Treatment .07 Oz
7.2

1. Orajel Touch-Free Cold Sore Patented Treatment .08 OZ

1
9.7/10 our score

  • Relieves pain* & itching
  • Clear, quick-dry formula
  • *for temporary topical pain relief
  • Cleans the affected area
  • Unique touch-free applicator

2. DocoShield Cold Sore Prevention Lip Balm w/Docosanol and Lysine (3-Pack)

2
9.5/10 our score

  • Also formulated with moisturizing ingredients such as jojoba oil, to ensure your lips stay clear and moisturized.
  • Now with l-lysine!
  • Like abreva, the active ingredient in docoshield is docosanol, an antiviral agent clinically proven to reduce the duration of cold sores caused by the herpes simplex virus. docosanol acts by preventing healthy cells from being infected by the virus, effectively stopping the virus from replicating and spreading.
  • Docoshield is the first regular use lip balm with docosanol, with over seven years of success eliminating cold sore outbreaks, and keeping lips well moisturized
  • Used regularly, this lip balm can prevent cold sore outbreaks.

3. Abreva Docosanol 10% Cream Pump, Only FDA Approved Treatment for Cold Sore/Fever Blister

3
9.1/10 our score

  • Healing cream for treating cold sores and fever blisters on the face or lips
  • Delivers best results when treated at the first tingle
  • Shortens the duration of tingling, pain, burning and itching symptoms
  • Penetrates deep into the skin to the source of the spreading virus
  • Contains 2 grams of cream

4. Abreva Docosanol Cold Sore Treatment 10% Cream Tube, Only FDA Approved Treatment

4
8.8/10 our score

  • Apply before cosmetics after the cold sore treatment has dried and remember to use a new applicator to prevent spreading of the virus
  • Abreva penetrates deep into the skin to the source of the spreading virus to block the virus and provide a barrier to protect healthy skin cells
  • This item contains 2 tubes of 2 gram cold sore cream for a total of 4 grams in the set
  • Abreva cold sore treatment helps heal cold sores and fever blisters on the face or lips of adults and children over 12 years
  • Abreva shortens the duration of tingling, pain, burning and itching symptoms associated with cold sores when used at the first sign
  • Based on laboratory studies

5. Abreva Cold Sore/Fever Blister Treatment, Pump 0.07 oz (2 g) (Abreva Pump)

5
8.6/10 our score

  • Docosanol 10% - cold sore/fever blister treatment

6. Lip Clear Lysine+ Cold Sore Treatment 0.25 oz

6
8.3/10 our score

  • Soothes and moisturizes
  • Stops burning and itching
  • Cuts healing time in half
  • Fast pain relief

7. Abreva Cold Sore & Fever Blister Treatment, .07 oz

7
8.1/10 our score

  • Healing cream for treating cold sores and fever blisters on face or lips

8. Cold Sores Begone Cold Sore Treatment 1 Stick 0.15 Ounce

8
7.8/10 our score

  • Our mission is "to meet consumer demand in a demanding world"
  • Unbeatable sale is a privately held direct marketing retailer
  • Our management shares more than 30 years of experience in direct marketing and consumer goods industries

9. Herpecin L Lip Balm Stick, SPF 30 & Lysine, 0.1 Ounce Tube

9
7.5/10 our score

  • Herpecin l for cold sores: uniquely formulated with dimethicone & lysine, herpecin helps relieve and protect painful cracking of lips and promotes healing of cold sores without numbing or drying.
  • Spf 30 protection: uv rays can increase your risk of sun cancer, chapped lips, early skin aging & damaged skin can promote the development of cold sores. herpecin l lip balm can help prevent sunburn.
  • Real relief from real medicine: herpecin l soothes, moisturizes and creates a spf 30 barrier to protect your lips against the sun's harmful uv rays. it does more for a cold sore.
  • Treat your lips: herpecin l is the answer to dry, chapped lips, cold sores, sun & fever blisters. its not waxy, making it easy to apply, giving you better relief from sores & blisters.
  • Herpecin l lip balm: herpecin l helps treat, protect and relieve cold sores, sun and fever blisters, and chapped lips. it's formulated with lysine, vitamins c, b6, and e, lemon balm and added spf 30 protection.

10. Abreva Cold Sore Treatment .07 Oz

10
7.2/10 our score

  • Abreva for cold sores

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