Best Cold Sore Treatment For Lips In May 2025

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In this article, we will present the top 10 Best Cold Sore Treatment For Lips available on the market, along with our expert reviews. Get one of them and have fun! You’ll love it!

To help you in your search, we have completed this list of the Best Cold Sore Treatment For Lips.

Top Rated Best Cold Sore Treatment For Lips Of 2025

Rank	Product Name	Score
1	Abreva Docosanol Cold Sore Treatment 10% Cream Tube, Only FDA Approved Treatment Buy Now	9.7 Buy Now
2	Orajel Touch-Free Cold Sore Patented Treatment .08 OZ Buy Now	9.5 Buy Now
3	Lip Clear Lysine+ Cold Sore Treatment 0.25 oz Buy Now	9.1 Buy Now
4	Abreva Docosanol 10% Cream Pump, Only FDA Approved Treatment for Cold Sore/Fever Blister Buy Now	8.8 Buy Now
5	DocoShield Cold Sore Prevention Lip Balm w/Docosanol and Lysine (3-Pack) Buy Now	8.6 Buy Now
6	Cold Sores Begone Cold Sore Treatment 1 Stick 0.15 Ounce Buy Now	8.3 Buy Now
7	Quantum Health Lip Clear Lysine+ Core Sore Treatment Ointment Buy Now	8.1 Buy Now
8	All-Natural Cold Sore Treatment – Pain Relief for Cold Sore – Cold Sore Buy Now	7.8 Buy Now
9	Herpecin L Lip Balm Stick, SPF 30 & Lysine, 0.1 Ounce Tube Buy Now	7.5 Buy Now
10	COLD SORE SHIELD Daily Cold Sore Defense / Prevention Supplement (60 Tablets) Immune Buy Now	7.2 Buy Now

1. Abreva Docosanol Cold Sore Treatment 10% Cream Tube, Only FDA Approved Treatment

• This item contains 2 tubes of 2 gram cold sore cream for a total of 4 grams in the set
• Based on laboratory studies
• Abreva shortens the duration of tingling, pain, burning and itching symptoms associated with cold sores when used at the first sign
• Abreva penetrates deep into the skin to the source of the spreading virus to block the virus and provide a barrier to protect healthy skin cells
• Abreva cold sore treatment helps heal cold sores and fever blisters on the face or lips of adults and children over 12 years
• Apply before cosmetics after the cold sore treatment has dried and remember to use a new applicator to prevent spreading of the virus

2. Orajel Touch-Free Cold Sore Patented Treatment .08 OZ

• Cleans the affected area
• Relieves pain* & itching
• *for temporary topical pain relief
• Clear, quick-dry formula
• Unique touch-free applicator

3. Lip Clear Lysine+ Cold Sore Treatment 0.25 oz

• Soothes and moisturizes
• Cuts healing time in half
• Fast pain relief
• Stops burning and itching

4. Abreva Docosanol 10% Cream Pump, Only FDA Approved Treatment for Cold Sore/Fever Blister

• Shortens the duration of tingling, pain, burning and itching symptoms
• Penetrates deep into the skin to the source of the spreading virus
• Healing cream for treating cold sores and fever blisters on the face or lips
• Delivers best results when treated at the first tingle
• Contains 2 grams of cream

5. DocoShield Cold Sore Prevention Lip Balm w/Docosanol and Lysine (3-Pack)

• Now with l-lysine!
• Also formulated with moisturizing ingredients such as jojoba oil, to ensure your lips stay clear and moisturized.
• Docoshield is the first regular use lip balm with docosanol, with over seven years of success eliminating cold sore outbreaks, and keeping lips well moisturized
• Like abreva, the active ingredient in docoshield is docosanol, an antiviral agent clinically proven to reduce the duration of cold sores caused by the herpes simplex virus. docosanol acts by preventing healthy cells from being infected by the virus, effectively stopping the virus from replicating and spreading.
• Used regularly, this lip balm can prevent cold sore outbreaks.

6. Cold Sores Begone Cold Sore Treatment 1 Stick 0.15 Ounce

• Our mission is "to meet consumer demand in a demanding world"
• Unbeatable sale is a privately held direct marketing retailer
• Our management shares more than 30 years of experience in direct marketing and consumer goods industries

7. Quantum Health Lip Clear Lysine+ Core Sore Treatment Ointment

• Experience instant relief - soothes and moisturizes, reduces pain, burning, and itching upon contact.
• Cuts cold sore healing time in half - 40% of participants in a southern california university of health sciences clinical study were fully cured of cold sore symptoms after 3 days.
• Innovative cold sore fighting formula - includes active ingredient menthol, which brings fast pain relief, and lysine, which inhibits the activity of arginine, a common trigger of cold sore outbreaks.
• Award winning brand - taste for life magazine gave our lip clear lysine+ ointment their essential supplements award in 2017.
• Our products work even better together - for optimal results, use in conjunction with our super lysine+ tablets

8. All-Natural Cold Sore Treatment – Pain Relief for Cold Sore – Cold Sore

• Prevent dry and chapped lips now you can go out without having to worry about chapped lips or fever blister! apply this cold sore lip balm now and get that soft and moisturize lips all day long!
• Effectively relieve pain cause by fever blisters get yourself a cold sore treatment that will efficiently relieve red, swollen, and sore lips! prevent your skin from breaking up that will cause discomfort and ache.
• Safe to use by the whole family get this cold sore treatment for you and your family! no need to buy different brands for the kids or adults as this product is great for children 2 years of age and older. you can even wear them underneath your makeup! leave them to dry before applying your normal cosmetics and you should be able to cover your blisters.
• Made from all-natural ingredient you can be sure that what you are applying on your fever blisters is safe to use as they are made from organic ingredients that are meant to heal your cold sore lip without causing you any discomfort.
• Handy and easy to carry bring this cold sore cream everywhere you go and use them as a lip balm to prevent dry lips and cold sore. place them inside your bag or on your first aid kit and keep them beside you all the time.

9. Herpecin L Lip Balm Stick, SPF 30 & Lysine, 0.1 Ounce Tube

• Herpecin l for cold sores: uniquely formulated with dimethicone & lysine, herpecin helps relieve and protect painful cracking of lips and promotes healing of cold sores without numbing or drying.
• Spf 30 protection: uv rays can increase your risk of sun cancer, chapped lips, early skin aging & damaged skin can promote the development of cold sores. herpecin l lip balm can help prevent sunburn.
• Herpecin l lip balm: herpecin l helps treat, protect and relieve cold sores, sun and fever blisters, and chapped lips. it's formulated with lysine, vitamins c, b6, and e, lemon balm and added spf 30 protection.
• Real relief from real medicine: herpecin l soothes, moisturizes and creates a spf 30 barrier to protect your lips against the sun's harmful uv rays. it does more for a cold sore.
• Treat your lips: herpecin l is the answer to dry, chapped lips, cold sores, sun & fever blisters. its not waxy, making it easy to apply, giving you better relief from sores & blisters.

10. COLD SORE SHIELD Daily Cold Sore Defense / Prevention Supplement (60 Tablets) Immune

• No more embarrassing cold sores: our cold sore defence helps you no longer live in fear of embarrassing cold sores and surprise breakouts. take daily (for best results) or start taking a few weeks before an important date, presentation, travel, or any other stressful event that you have experienced cold sores in the past. imagine life, cold sore free.
• Powerful ingredients: combination of potent immune supporting nutrients including zinc, selenium, vitamin c, l lysine and more. all made and manufactured in the u.s.a!
• Buy with confidence: buy our cold sore prevention tablets worry free! dont love them? simply return them!
• Daily supplement: taken daily, or just weeks before a stressful event, important date, travel etc, cold sore shield helps the defence of cold sore breakouts.
• Immune system boost: cold sore shield's lip blister treatment works with the body's immune system to support its daily defense of cold sores*