Best Expectorant In February 2025

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Here, we’ll review the top 10 Best Expectorant on the market today. We’ll provide an overview of the pros and cons of each product. Read on for our selection of Best Expectorant.

To help you in your search, we have completed this list of the Best Expectorant.

Top Rated Best Expectorant Of 2025

Rank	Product Name	Score
1	Chest Congestion, Mucinex 12 Hour Extended Release Tablets, 100ct, 600 mg Guaifenesin Relieves Buy Now	9.7 Buy Now
2	Guardian Mucus Relief 12 Hour Extended Release, 1200mg 56ct Maximum Strength Guaifenesin, Chest Buy Now	9.5 Buy Now
3	Chest Congestion, Mucinex 12 Hour Extended Release Tablets, 68ct, 600 mg Guaifenesin Relieves Buy Now	9.1 Buy Now
4	Kirkland Signature Mucus Relief Chest Guaifenesin 400 mg Expectorant - 200 Immediate Release Buy Now	8.8 Buy Now
5	Chest Congestion, Mucinex 12 Hour Extended Release Tablets, 40ct, 600 mg Guaifenesin Relieves Buy Now	8.6 Buy Now
6	Kirkland Signature Mucus Relief Chest Expectorant (Guaifenesin 400 Mg), 2 bottles of 200-Count Buy Now	8.3 Buy Now
7	Guardian Mucus ER 12 Hour Extended Release Guaifenesin, 40ct 600mg, Chest Congestion Expectorant Buy Now	8.1 Buy Now
8	ValuMeds Mucus Relief Caplets Guaifenesin 400mg (200 Caplets) | Chest Congestion and Decongestant Buy Now	7.8 Buy Now
9	Guardian Mucus ER 12 Hour Extended Release Guaifenesin, 1200mg 28ct Maximum Strength, Chest Buy Now	7.5 Buy Now
10	Robitussin Maximum Strength Cough and Chest Congestion DM Non-Drowsy Liquid Box, 8 Fluid Buy Now	7.2 Buy Now

1. Chest Congestion, Mucinex 12 Hour Extended Release Tablets, 100ct, 600 mg Guaifenesin Relieves

• Stock up and save: did you know, if you use mucinex 12 hour often you can and save when you buy higher count packs
• One easy pill: a unique bi-layer tablet, one layer for immediate release, the other layer for extended release so the medicine starts to release right away and lasts for up to 12 hours
• Trust mucinex: mucinex is the #1 doctor recommended otc expectorant and the #1 cold & cough brand doctors trust for themselves & their families
• Symptoms treated: relieves chest congestion caused by excess mucus by making your cough more productive
• Ingredients: guaifenesin (600 mg) is an expectorant that helps reduce chest congestion caused by colds, infections or irritants
• Mucinex 12 hour extended-release bi-layer tablets: clinically proven to last up to 12 hours, it provides powerful relief for your chest congestion

2. Guardian Mucus Relief 12 Hour Extended Release, 1200mg 56ct Maximum Strength Guaifenesin, Chest

• Makes coughs more productive
• Thins and loosens mucus
• Relieves chest congestion
• 1200mg 28 x 2 (total 56) count. compare to mucus relief 1200mg extended release bi-layer tablets
• Extended release. gets to work right away and each pill lasts 12 hours

3. Chest Congestion, Mucinex 12 Hour Extended Release Tablets, 68ct, 600 mg Guaifenesin Relieves

• Mucinex 12 hour extended-release bi-layer tablets: clinically proven to last up to 12 hours, it provides powerful relief for your chest congestion
• Stock up and save: did you know, if you use mucinex 12 hour often you can and save when you buy higher count packs
• Symptoms treated: relieves chest congestion caused by excess mucus by making your cough more productive
• Ingredients: guaifenesin (600 mg) is an expectorant that helps reduce chest congestion caused by colds, infections or irritants
• Trust mucinex: mucinex is the #1 doctor recommended otc expectorant and the #1 cold & cough brand doctors trust for themselves & their families
• One easy pill: a unique bi-layer tablet, one layer for immediate release, the other layer for extended release so the medicine starts to release right away and lasts for up to 12 hours

4. Kirkland Signature Mucus Relief Chest Guaifenesin 400 mg Expectorant - 200 Immediate Release

• 200 immediate release tablets
• Makes coughs more productive
• Thins and loosens mucus
• Relieves chest congestion
• Works like mucinex & robitussin at a fraction of the cost

5. Chest Congestion, Mucinex 12 Hour Extended Release Tablets, 40ct, 600 mg Guaifenesin Relieves

• One easy pill: a unique bi-layer tablet, one layer for immediate release, the other layer for extended release so the medicine starts to release right away and lasts for up to 12 hours
• Stock up and save: did you know, if you use mucinex 12 hour often you can and save when you buy higher count packs
• Mucinex 12 hour extended-release bi-layer tablets: clinically proven to last up to 12 hours, it provides powerful relief for your chest congestion
• Trust mucinex: mucinex is the #1 doctor recommended otc expectorant and the #1 cold & cough brand doctors trust for themselves & their families
• Symptoms treated: relieves chest congestion caused by excess mucus by making your cough more productive
• Ingredients: guaifenesin (600 mg) is an expectorant that helps reduce chest congestion caused by colds, infections or irritants

6. Kirkland Signature Mucus Relief Chest Expectorant (Guaifenesin 400 Mg), 2 bottles of 200-Count

• Mucus relief
• Relieves chest congestion
• Makes cough more productive
• 2 bottles of 200 tablets
• Thins and loosens mucus
• Works like mucinex and robitussin at a fraction of the cost!

7. Guardian Mucus ER 12 Hour Extended Release Guaifenesin, 40ct 600mg, Chest Congestion Expectorant

• Relieves chest congestion
• 600mg 40 count. compare to mucinex exteneded release bi layer tablets. blue dye free
• Thins and loosens mucus
• Makes coughs more productive
• Extended release. gets to work right away and each pill lasts 12 hours

8. ValuMeds Mucus Relief Caplets Guaifenesin 400mg (200 Caplets) | Chest Congestion and Decongestant

• Long-lasting, extended support offer 4 hour continuous relief, our mucus and nasal decongestant is a powerful expectorant that promotes clearer breathing.
• Proactive dual-layer these bi-layer caplets help treat chest congestion symptoms with an immediate-release layer and extended-release layer for ideal support.
• Breathe a little easier loosening up phlegm and thin bronchial secretions makes coughs more productive to help you breathe more clearly with less heavy tension.
• Fast-acting chest congestion relief these 400mg mucus relief sinus caplets provide day and night extended release support to loosen and thin phlegm buildup.
• Easy-to-swallow capsules small in size but big in power, enjoy cough mucus relief with tablets that can be used by those with allergies, colds, infections, and flu bugs.

9. Guardian Mucus ER 12 Hour Extended Release Guaifenesin, 1200mg 28ct Maximum Strength, Chest

• Thins and loosens mucus
• Extended release. gets to work right away and each pill lasts 12 hours
• Relieves chest congestion
• 1200mg 28 count. compare to mucus relief 1200mg extended release bi-layer tablets
• Makes coughs more productive

10. Robitussin Maximum Strength Cough and Chest Congestion DM Non-Drowsy Liquid Box, 8 Fluid

• Robitussin adult maximum strength cough + chest congestion dm max (8 fl. oz. bottle), non-drowsy cough suppressant & expectorant, raspberry flavor
• Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
• Hsa and fsa eligible product
• Suitable for adults and children 12 years and over
• Maximum-strength formula with expectorant that thins and loosens mucus for productive coughs
• Cough suppressant for non-drowsy control and relief for cough and an expectorant for relief of chest congestion