Best Laundry Stain Remover For Set In Stains In April 2025

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To help you choose the Best Laundry Stain Remover For Set In Stains, we’ve put together this comprehensive guide. We have tried to cover as much variety as possible. Hope you will find it helpful!

To help you in your search, we have completed this list of the Best Laundry Stain Remover For Set In Stains.

Top Rated Best Laundry Stain Remover For Set In Stains Of 2025

Rank Product Name Score
1
OxiClean Versatile Stain Remover Powder, 7.22 lbs
OxiClean Versatile Stain Remover Powder, 7.22 lbs
9.7
2
Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor
Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor
9.5
3
Shout Advanced Spray and Wash Laundry Stain Remover Gel, Best Shout Formula, 22
Shout Advanced Spray and Wash Laundry Stain Remover Gel, Best Shout Formula, 22
9.1
4
Puracy Natural Laundry Stain Remover, Enzyme Odor Eliminator, Free & Clear, 25 Ounce
Puracy Natural Laundry Stain Remover, Enzyme Odor Eliminator, Free & Clear, 25 Ounce
8.8
5
Shout Advanced Ultra Concentrated Gel Set-In Stain Brush Laundry Stain Remover , 8.7
Shout Advanced Ultra Concentrated Gel Set-In Stain Brush Laundry Stain Remover , 8.7
8.6
6
Nature’s Miracle P-98174 Set-In Stain Destroyer Dog 32 Ounces, Oxy Formula With Orange
Nature’s Miracle P-98174 Set-In Stain Destroyer Dog 32 Ounces, Oxy Formula With Orange
8.3
7
Emergency Stain Rescue Stain Remover Spray Carpet Stain Remover Spray
Emergency Stain Rescue Stain Remover Spray Carpet Stain Remover Spray
8.1
8
Dreft Blissfuls In-Wash Scent Booster Beads, Baby Fresh, 14.8 Ounce
Dreft Blissfuls In-Wash Scent Booster Beads, Baby Fresh, 14.8 Ounce
7.8
9
Shout Spray and Wash Advanced Action Stain Remover for Clothes, 22 oz
Shout Spray and Wash Advanced Action Stain Remover for Clothes, 22 oz
7.5
10
Zout Laundry Stain Remover Spray, Triple Enzyme Formula, 22 Ounce
Zout Laundry Stain Remover Spray, Triple Enzyme Formula, 22 Ounce
7.2

1. OxiClean Versatile Stain Remover Powder, 7.22 lbs

1
9.7/10 our score

  • Works on carpets, upholstery and nearly any surface in your home
  • Chlorine-free and color safe formula
  • Works with regular detergent to get clothes extra clean
  • One 7.22 lb. box of oxiclean versatile stain remover powder
  • Oxygen-based, water-activated formula gets out tough dirt, persistent spots and set-in stains

2. Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor

2
9.5/10 our score

  • Certified gentle and safe chlorine free and color safe. safe to use around pets and children. no hazardous propellants, no residue left behind. so gentle its been certified safe for all carpets, earning the seal of approval by the trusted carpet and rug institute (cri)
  • Enzyme activated the key is getting to the problem deep-down. this spray contains natural enzymatic bacteria that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated.
  • Eliminates stains, odors and residue if its gross, its gone. not just the stain, but the stink. from stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all.
  • Every surface, every time for use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas -- anywhere stains happen.
  • 100% satisfaction guaranteed an amazon best seller for a reason. if your stains and odors arent gone, neither is your money. well refund it in full

3. Shout Advanced Spray and Wash Laundry Stain Remover Gel, Best Shout Formula, 22

3
9.1/10 our score

  • Formula lets you treat stains now and wash up to a week later
  • This super-concentrated gel is specially formulated to tackle those stubborn, set-in stains and works great on everyday stains, too.
  • Stain remover spray built with a convenient, easy-to-use trigger.
  • Safe for all colorfast washables and works in all water temperatures
  • 70% more stain-fighting surfactants to treat difficult, set-in stains.

4. Puracy Natural Laundry Stain Remover, Enzyme Odor Eliminator, Free & Clear, 25 Ounce

4
8.8/10 our score

  • Guaranteed to be the most effective stain remover youve ever used
  • Safely removes any type of stain: natural ingredients, hypoallergenic, gluten-free, non-toxic, non-bleaching, biodegradable, vegan, certified cruelty-free
  • Natural formula is safe for your family, dark colors, delicate fabrics, grey water and septic systems, and the environment, never tested on animals, 100% satisfaction guaranteed, made in the usa!
  • We donate: for every sale, we donate our natural & organic products to children and families that are less fortunate
  • Completely eliminates grass, berries, blood, sweat, oil, tomato sauce, watermelon, red wine, mud, cosmetics, pet accidents, and hundreds of other stains and odors, effective on clothing, linens, carpets, floor mats, dress shirts, bedding, car seats, cloth diapers and other washable fabrics

5. Shout Advanced Ultra Concentrated Gel Set-In Stain Brush Laundry Stain Remover , 8.7

5
8.6/10 our score

  • Safe for all colorfast washables
  • Built-in brush makes treating stains easy. (pack of 1)
  • Formula lets you treat stains now and wash up to a week later
  • Thick gel formula concentrates stain-lifting power directly onto the stain

6. Nature’s Miracle P-98174 Set-In Stain Destroyer Dog 32 Ounces, Oxy Formula With Orange

6
8.3/10 our score

  • Age range description: all life stages
  • Oxy formula: oxygen concentrate penetrates, separates and lifts embedded stains and odors.
  • Destroys set-in stains: use for even deep-set stains and severe, old or stubborn odors.
  • Fresh orange scent: dog odor control formula gets your home smelling clean again.
  • Trusted brand: from the maker of natures miracle products, the pet stain and odor removing brand you trust because it works!
  • Safe for pets and home: when used and stored as directed, this formula can be used around your pets.

7. Emergency Stain Rescue Stain Remover Spray Carpet Stain Remover Spray

7
8.1/10 our score

  • A household essential - a spot cleaning stain remover spray specifically designed to quickly & safely treat the inevitable stains made by messy kids, house guests and dinner time accidents.
  • Nothing nasty, no compromise, a safer choice. no peroxide, no chlorine, no phosphates or parabens, the 100% biodegradable surfactant and ph neutral formula is tough on stains not on skin, clothes or the environment. safer choice certified.
  • Fast, powerful & clean emergency stain rescues concentrated formula magically removes food and other stains from clothing, bibs, cloth diapers, furniture, carpets, linens, car interiors, sofas and upholstery and many more.
  • For all kinds of stains. this universal spot remover is remarkably effective on all types of fresh and set-in stains, on food berries, fruits, juice, baby food, formula, ice-cream, carrots, ketchup and spaghetti sauce. an excellent blood stain remover for all stubborn and nasty stains.
  • Recommended and reviewed. 5 star reviews from the today show, the view, good morning america, real simple, gq and thousands of happy and appreciative users.

8. Dreft Blissfuls In-Wash Scent Booster Beads, Baby Fresh, 14.8 Ounce

8
7.8/10 our score

  • Designed to completely dissolve in water
  • For all stages of childhood
  • Long lasting baby fresh scent
  • In-wash scent booster
  • Specially designed to complement draft detergent

9. Shout Spray and Wash Advanced Action Stain Remover for Clothes, 22 oz

9
7.5/10 our score

  • Works in all water temperatures
  • 70percentage more stain fighting surfactants to treat difficult, set in stains
  • This super concentrated gel is specially formulated to tackle those stubborn, set in stains and works great on everyday stains too
  • Safe for all colorfast washables
  • Convenient, easy to use trigger

10. Zout Laundry Stain Remover Spray, Triple Enzyme Formula, 22 Ounce

10
7.2/10 our score

  • The first enzyme helps remove tough protein stains such as blood, grass, and sweat
  • Triple threat stains need triple enzyme formula!
  • The second enzyme works on starch stains like tomato and bbq sauces.
  • The third enzyme targets oily stains like salad dressing and margarine.
  • This package includes on 22 ounce bottle of zout laundry stain remover

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