Best Nasal Spray For Colds In May 2025

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There is always a perfect Best Nasal Spray For Colds out there in the market for you. However, you may not have the time and resources to try and research each of them in detail. So we’ve done the heavy lifting and are sharing below our detailed review of Top 10 Best Nasal Spray For Colds.

To help you in your search, we have completed this list of the Best Nasal Spray For Colds.

Top Rated Best Nasal Spray For Colds Of 2025

Rank	Product Name	Score
1	Vicks Sinex SEVERE Original Ultra Fine Mist Sinus Nasal Spray Decongestant for Fast Buy Now	9.7 Buy Now
2	XLEAR Nasal Spray, 1.5 Fl Oz, All-Natural Saline and Xylitol Moisturizing Sinus Care Buy Now	9.5 Buy Now
3	Neo-Synephrine Nasal Spray for Cold & Sinus Relief, Regular Strength, Fast Relief, Pharmacist Buy Now	9.1 Buy Now
4	Sinus & Allergy Fast Acting Nasal Congestion Relief Spray, Mucinex Sinus Max Buy Now	8.8 Buy Now
5	Vicks Sinex Severe No Drip Sinus Congestion Nasal Spray, 0.5 fl oz Buy Now	8.6 Buy Now
6	Vicks Sinex Severe Sinus Congestion Nasal Spray, 0.5 fl oz - Moisturizing Ultra Buy Now	8.3 Buy Now
7	Vicks Sinex Severe Original Sinus Nasal Spray Decongestant, 0.5 fl oz (4 Pack) Buy Now	8.1 Buy Now
8	Zicam Cold Remedy No-Drip Nasal Spray, Shortens Colds, 0.5 Ounce Buy Now	7.8 Buy Now
9	Zicam No Drip Liquid Nasal Gel with Soothing Aloe Vera, Extreme Congestion Relief Buy Now	7.5 Buy Now
10	Basic Care Premium Saline Nasal Moisturizing Spray, Twin Pack, 6 Ounces Total Buy Now	7.2 Buy Now

1. Vicks Sinex SEVERE Original Ultra Fine Mist Sinus Nasal Spray Decongestant for Fast

• Sinus pressure relief. effective nasal spray decongestant that relieves sinus pressure and shrinks swollen nasal membranes
• For colds and allergies. over-the-counter nasal spray that helps relieve the nasal stuffiness that often accompanies colds, hay fever, or upper respiratory allergies
• Ultra fine mist. clear your head with an ultra fine mist and powerful vicks vapors
• Breathe freely fast. provides powerful sinus congestion relief in seconds so you can breathe freely
• 12 hour relief. works for up to 12 hours for long-lasting relief of nasal stuffiness and sinus pressure

2. XLEAR Nasal Spray, 1.5 Fl Oz, All-Natural Saline and Xylitol Moisturizing Sinus Care

• Improved formula with xylitol: our patented saline nasal spray solution reduces tissue inflammation and naturally opens airways. xylitol's powerful oral and upper respiratory health benefits come from its unique five-carbon structure. xylitol helps to reduce swelling and allergy symptoms by reducing bacterial adhesion on you nasal tissue.
• Easy to use directions: clear the nasal passageway by gently blowing your nose before using xlear. prime the pump by holding the sinus rinse bottle upright and pumping one or more times until the saline solution is dispensed. insert nozzle into nostril and depress pump completely while breathing in through your nose. spray each nostril 2-4 times and use at least twice d...
• Natural saline solution & nasal rinse: our nasal saline spray will gently clean and moisturize the sinus tissues. unlike other normal saline nasal sprays our spray also acts as a nasal decongestant by targeting the primary causes of nasal congestion. our nose spray will help reduce tissue swelling from pollen, pollution, bacteria and all other irritants.
• Safe nasal rinse & spray: our all natural nasal cleaner is safe for kids, non-addictive and non gmo project verified and is effective without the use of steroids, drugs or chemicals. its the ideal daily sinus medicine that will reduce swelling and open your airways. use our saline nose spray before bed to help reduce snoring.
• Fast sinus pressure relief: our natural saline nasal spray will wash away pollutants and help to bring relief to chronic sinus infection. use our sinus spray daily to protect and keep your nasal passages clean. each 1.5 oz bottle delivers approx. 240 fine mist sprays so you can find fast and quick relief.

3. Neo-Synephrine Nasal Spray for Cold & Sinus Relief, Regular Strength, Fast Relief, Pharmacist

• Immediate 4 hour nasal congestion relief
• 0.5% phenylephrine hcl nasal decongestant
• Pharmacist-recommended
• Adults and children 12 years and older
• With the highest level of acid ingredient
• No one knows noses like neo-synephrine

4. Sinus & Allergy Fast Acting Nasal Congestion Relief Spray, Mucinex Sinus Max

• Uses: temporarily relieves nasal congestion due to a cold, hay fever or other upper respiratory allergies. promotes nasal & sinus drainage. temporarily relieves sinus congestion and pressure. helps clear nasal passages, shrinks swollen membranes.
• Also available from mucinex: mucinex sinus-max clear & cool nasal spray for severe nasal congestion relief.
• Key benefits: fast acting relief that lasts for up to 12 hours, non-drowsy and nasal congestion relief due to upper respiratory allergies or hay fever.
• Long lasting: lasts up to 12 hours, through the day or night.
• What is it: this nasal spray (0.75 fl oz per bottle) provides targeted nasal congestion relief due to upper respiratory allergies or hay fever. active ingredient: oxymetazoline hydrochloride 0.05%.

5. Vicks Sinex Severe No Drip Sinus Congestion Nasal Spray, 0.5 fl oz

• Breathe freely fast
• Starts working instantly for up to 12 hours
• For fast, long lasting relief from sinus pressure and nasal stuffiness
• Effective nasal spray decongestant that relieves sinus pressure and shrinks swollen nasal membranes
• Provides powerful congestion relief and prevents dripping down nose and throat

6. Vicks Sinex Severe Sinus Congestion Nasal Spray, 0.5 fl oz - Moisturizing Ultra

• Vicks sinex moisturizing 12 hour contains an effective decongestant for fast, long lasting relief of nasal stuffiness
• From the makers of vicks
• The sinus congestion & pressure, to clear your head, medicine
• It is an effective nasal spray decongestant that relieves sinus pressure and shrinks swollen nasal membranes so you can breathe more freely
• Nothing clears your head faster

7. Vicks Sinex Severe Original Sinus Nasal Spray Decongestant, 0.5 fl oz (4 Pack)

• Sinus pressure relief. effective nasal spray decongestant that relieves sinus pressure and shrinks swollen nasal membranes
• For colds and allergies. over-the-counter nasal spray that helps relieve the nasal stuffiness that often accompanies colds, hay fever, or upper respiratory allergies
• Breathe freely fast. provides powerful sinus congestion relief in seconds so you can breathe freely
• Unbeatable confestion relief among otc topical nasal decongestant sprays and from the makers of vicks
• 12 hour relief. works for up to 12 hours for long-lasting relief of nasal stuffiness and sinus pressure

8. Zicam Cold Remedy No-Drip Nasal Spray, Shortens Colds, 0.5 Ounce

• Multi-symptom cold relief: zicam's plant-based formula provides multi-symptom cold relief to hep open your nasal passages, so you feel better, faster. help calm your cold with zicam cold remedy products like nasal spray & swabs or our rapidmelt tablets.
• Homeopathic zinc spray: our homeopathic nasal spray is clinically proven to shorten a cold when taken at the first sign of sniffles, sneezes, or coughs. this nasal spray is easy to use & non-drowsy, for a homeopathic cold remedy you can take anywhere.
• Zicam for shorter colds: zicam homeopathic cold remedy is meant to be used in the beginning of a cold. try zicam the next time you feel the first sniffle, sneeze or cough of an oncoming cold. satisfaction guaranteed.
• Zicam homeopathic remedies: known for zicam cold remedy products, we also offer products for homeopathic allergy relief, homeopathic cold relief for kids, & nasal congestion & sinus relief. store at room temperature - 15 to 29 degree celsius
• Zicam cold remedy nasal spray zinc-free: our zinc-free, homeopathic nasal spray helps relieve cold symptoms & nasal congestion, contains cooling menthol & soothing aloe vera. get better faster with zicam cold remedy, #1 pharmacist recommended brand.*

9. Zicam No Drip Liquid Nasal Gel with Soothing Aloe Vera, Extreme Congestion Relief

• Nasal congestion & sinus relief: are nasal congestion or sinus pressure getting you down? try zicam's no-drip liquid nasal spray for up to 12 hours of non-drowsy relief from nasal congestion and sinus pressure due to colds or allergy symptoms.
• No-drip nasal spray: zicam's no drip liquid nasal spray is formulated so that it won't drip down your throat, unlike many nasal sprays. get relief from nasal congestion or sinus pressure, without the aftertaste of many saline nasal sprays.

10. Basic Care Premium Saline Nasal Moisturizing Spray, Twin Pack, 6 Ounces Total

• Caution: keep basic care premium saline nasal moisturizing spray out of reach of children. the use of this nasal moisturizing spray dispenser by more than one person may spread infection.
• Compare and save: compare to the ingredients in ocean. basic care premium saline nasal moisturizing spray contains sodium chloride 0.65%, phenylcarbinol and benzalkonium chloride as preservatives.
• Soothes dry nasal passages: this saline nasal spray relieves dry nasal membranes.
• Saline nasal spray provides non-medicated relief for irritated and dry nasal passages.
• Relieves dryness from allergy, sinus and cold medications. instantly soothes dry nasal passages.