Best Sinus Medicine For Adults Day And Night In February 2025

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If you are looking for the Best Sinus Medicine For Adults Day And Night of top quality, read our detailed reviews on them here before making the purchase decision.

To help you in your search, we have completed this list of the Best Sinus Medicine For Adults Day And Night.

Top Rated Best Sinus Medicine For Adults Day And Night Of 2025

Rank	Product Name	Score
1	Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 36 ct Buy Now	9.7 Buy Now
2	Sinus & Allergy Fast Acting Nasal Congestion Relief Spray, Mucinex Sinus Max Buy Now	9.5 Buy Now
3	Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant, 24 ct Buy Now	9.1 Buy Now
4	Alka-Seltzer Plus Maximum Strength Powermax Liquid Gels, Severe Sinus, Allergy & Cough, 24 Buy Now	8.8 Buy Now
5	Tylenol Sinus + Headache Non-Drowsy Daytime Caplets with Acetaminophen & Phenylephrine HCl, 24 Buy Now	8.6 Buy Now
6	Mucinex Sinus-Max Max Strength Day & Night Caplets 20 ct Buy Now	8.3 Buy Now
7	Alka-Seltzer Plus Maximum Strength Powermax Liquid Gels, Sinus & Cold Day & Night Buy Now	8.1 Buy Now
8	Mucinex Sinus-Max Max Strength Day & Night Liquid Gels (24ct) Relieves Sinus Pressure Buy Now	7.8 Buy Now
9	Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count Buy Now	7.5 Buy Now
10	Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant Tablets, 20 ct Buy Now	7.2 Buy Now

1. Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 36 ct

• The maximum strength formula helps clear sinus congestion and relieve sinus pressure due to the common cold, hay fever or other upper respiratory allergies
• 36-count of sudafed pe sinus congestion maximum strength non-drowsy tablets for fast, powerful relief of sinus pressure and sinus and nasal congestion
• Each coated tablet contains 10 milligrams of phenylephrine hcl, a nasal decongestant that provides non-drowsy symptom relief
• From the #1 pharmacist recommended brand among oral otc decongestants, this non-drowsy decongestant can be used by adults and children 12 years and older for fast, powerful relief
• This sinus congestion & pressure relief medicine also helps reduce nasal swelling to help you breathe easier, and can be taken every 4 hours as necessary for effective relief of cold and allergy symptoms

2. Sinus & Allergy Fast Acting Nasal Congestion Relief Spray, Mucinex Sinus Max

• Uses: temporarily relieves nasal congestion due to a cold, hay fever or other upper respiratory allergies. promotes nasal & sinus drainage. temporarily relieves sinus congestion and pressure. helps clear nasal passages, shrinks swollen membranes.
• Also available from mucinex: mucinex sinus-max clear & cool nasal spray for severe nasal congestion relief.
• Long lasting: lasts up to 12 hours, through the day or night.
• Key benefits: fast acting relief that lasts for up to 12 hours, non-drowsy and nasal congestion relief due to upper respiratory allergies or hay fever.
• What is it: this nasal spray (0.75 fl oz per bottle) provides targeted nasal congestion relief due to upper respiratory allergies or hay fever. active ingredient: oxymetazoline hydrochloride 0.05%.

3. Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant, 24 ct

• 24-count box of sudafed pe sinus pressure + pain relief maximum strength non-drowsy decongestant tablets provide powerful relief of sinus pain, sinus pressure, nasal congestion and headaches
• This sinus congestion & pain medicine also temporarily relieves nasal congestion associated with hay fever, upper respiratory allergies and the common cold
• The non-drowsy decongestant helps promotes sinus drainage, temporarily reduces fever and helps relieve headaches and minor aches and pain
• Each caplet contains 5 milligrams of the decongestant phenylephrine hcl and 325 milligrams of acetaminophen, a pain reliever and fever reducer
• From the #1 pharmacist recommended brand among oral otc decongestants, this maximum strength formula can be used by adults and children 12 years and older for powerful symptom relief

4. Alka-Seltzer Plus Maximum Strength Powermax Liquid Gels, Severe Sinus, Allergy & Cough, 24

• Covered by bayer healthcare llc-consumer health 60-day satisfaction guarantee.
• Powerful, multi-symptom relief for your worst allergies, including sinus congestion, headache, sneezing, cough, sinus pressure, runny nose, and itchy, watery eyes
• Get the fast , effective allergy symptom relief you need, when you need it
• New 25% smaller pill: alka-seltzer plus maximum strength severe sinus, allergy & cough powermax gels have a concentrated formula to provide powerful fast relief
• Fast relief so you can get back to your busy life. use as directed.

5. Tylenol Sinus + Headache Non-Drowsy Daytime Caplets with Acetaminophen & Phenylephrine HCl, 24

• Pain reliever and decongestant formulated to temporarily relieve symptoms of nasal congestion, sinus headache and pressure
• 24-count box of tylenol sinus + headache daytime caplets for non-drowsy sinus symptom relief due to the common cold, hay fever or other respiratory allergies
• The non-drowsy formula of this sinus medicine provides effective daytime symptom relief by promoting sinus drainage and helping to decongest sinus openings and passages
• From the #1 doctor-recommended pain relief brand, these sinus relief caplets are suitable for adults and children ages 12 years and older
• Each caplet contains 325 mg of acetaminophen to temporarily relieve pain and reduce fever as well as 5 mg of phenylephrine hcl, a nasal decongestant to help clear nasal passages

6. Mucinex Sinus-Max Max Strength Day & Night Caplets 20 ct

• 20 count (12ct day time caplets, 8ct night time caplets)
• Day time: relieves sinus pressure, congestion, headache, and thins and loosens mucus
• Maximum strength formula
• Night time: relieves nasal congestion, sinus pressure, pain, runny nose, sneezing, and controls cough

7. Alka-Seltzer Plus Maximum Strength Powermax Liquid Gels, Sinus & Cold Day & Night

• Powerful relief, day or night, from your worst sinus & cold symptoms
• Take back your day with fast, effective cold and sinus medicine in one
• Relieve your worst symptoms of nasal & sinus congestion, mucus, headache, body pain and cough. use as directed.
• Covered by bayer healthcare llc-consumer health 60-day satisfaction guarantee.
• New 25% smaller pill: alka-seltzer plus maximum strength sinus & cold powermax gels have a concentrated formula to provide powerful fast relief

8. Mucinex Sinus-Max Max Strength Day & Night Liquid Gels (24ct) Relieves Sinus Pressure

• Night time: relieves nasal congestion, sinus pressure, pain, runny nose, sneezing, and controls cough
• Maximum strength formula
• 24 count (16ct day time liquid gels, 8ct night time liquid gels)
• Day time: relieves sinus pressure, congestion, headache, and thins and loosens mucus
• Fast dissolving liquid gels

9. Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count

• Nighttime cold and flu medicine provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains.
• Active ingredients: daytime cold & flu relief contains acetaminophen (pain reliever/fever reducer), dextromethorphan hbr (cough suppressant) and phenylephrine hcl (nasal decongestant) which compares to the active ingredients in vicks dayquil cold & flu. nighttime cold & flu relief contains acetaminophen (pain reliever/fever reducer), dextromethorphan hbr (cough suppre...
• Non-drowsy daytime cold and flu medicine provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains.
• Cold and flu symptoms: influenza (flu) and the common cold are respiratory illnesses caused by viruses. the cold has a gradual onset of symptoms, such as cough, sore throat and runny or stuffy nose. the flu has a sudden onset of symptoms, such as a fever over 100.4f, headache, nasal congestion, sore throat, fatigue and weakness, chills and sweats, and aching muscles, e...
• Pain reliever and fever reducer: both daytime and nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat.

10. Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant Tablets, 20 ct

• 20-count of sudafed pe sinus congestion day + night maximum strength decongestant tablets to temporarily relieve sinus pressure and sinus congestion for both day and night
• Each daytime and nighttime dose contains 10 milligrams of the nasal decongestant phenylephrine hcl and each nighttime dose also contains 25 milligrams of the antihistamine diphenhydramine hcl
• Both formulas help relieve sinus pressure and sinus congestion, and nasal congestion due to the common cold, hay fever, or upper respiratory allergies. nighttime tablets also relieve sneezing, runny nose, itchy, watery eyes and itchy throat or nose.
• Each multi-pack contains 20 tablets of nasal decongestant, with 12 daytime and 8 nighttime tablets for powerful symptom relief throughout the day and while you sleep
• From the #1 pharmacist recommended brand among oral otc decongestants, this maximum-strength formula can be used by adults and children 12 years and older for powerful relief