Best Pet Enzyme In May 2025

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It is not an easy task to choose the Best Pet Enzyme if you aren’t a frequent buyer. But don’t worry – we have compiled here the perfect list of Top 10 Best Pet Enzyme for you. Have a look at our list and choose the ones you like the most.

To help you in your search, we have completed this list of the Best Pet Enzyme.

Top Rated Best Pet Enzyme Of 2025

Rank Product Name Score
1
Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor
Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor
9.7
2
AmazonCommercial - 21 Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
AmazonCommercial - 21 Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
9.5
3
BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain
BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain
9.1
4
Bubbas Super Strength Concentrate Pet Odor Eliminator Carpet Shampoo Solution | Odor
Bubbas Super Strength Concentrate Pet Odor Eliminator Carpet Shampoo Solution | Odor
8.8
5
Professional Strength Stain & Odor Remover - Natural Enzyme Cleaner (Bulk 32oz)
Professional Strength Stain & Odor Remover - Natural Enzyme Cleaner (Bulk 32oz)
8.6
6
Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator | Urine Odor Remover
Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator | Urine Odor Remover
8.3
7
ANGRY ORANGE 24 oz Ready-to-Use Citrus Pet Odor Eliminator Pet Spray - Urine
ANGRY ORANGE 24 oz Ready-to-Use Citrus Pet Odor Eliminator Pet Spray - Urine
8.1
8
Nature’s Miracle Stain and Odor Remover Dog, Odor Control Formula
Nature’s Miracle Stain and Odor Remover Dog, Odor Control Formula
7.8
9
BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain
BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain
7.5
10
ANGRY ORANGE - Best Enzyme Pet Odor Eliminator and Stain Remover to Destroy
ANGRY ORANGE - Best Enzyme Pet Odor Eliminator and Stain Remover to Destroy
7.2

1. Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor

1
9.7/10 our score

  • Every surface, every time for use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas -- anywhere stains happen.
  • Eliminates stains, odors and residue if its gross, its gone. not just the stain, but the stink. from stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all.
  • Certified gentle and safe chlorine free and color safe. safe to use around pets and children. no hazardous propellants, no residue left behind. so gentle its been certified safe for all carpets, earning the seal of approval by the trusted carpet and rug institute (cri)
  • 100% satisfaction guaranteed an amazon best seller for a reason. if your stains and odors arent gone, neither is your money. well refund it in full
  • Enzyme activated the key is getting to the problem deep-down. this spray contains natural enzymatic bacteria that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated.

2. AmazonCommercial - 21 Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack

2
9.5/10 our score

  • 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments
  • Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results
  • Non-corrosive, non-flammable, non-acidic, and non-caustic with a fresh mint scent
  • Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more
  • Ideal for commercial properties, retail, and hospitality

3. BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain

3
9.1/10 our score

  • Best professional grade cleaning solution: scientifically formulated to be more potent than other pet odor enzyme cleaners for your flooring, upholstery, area rugs and carpets, yet safe to use around kids and pets. permanently destroys pet enzyme odors and stains
  • Satisfaction guaranteed: other pet odor enzyme sprays use active bacteria that are ineffective soon after you buy them. bubba's dormant bacteria formula is the best premium deep cleaning stain and pet urine enzyme carpet cleaner or your money back
  • Pet stain and odor miracle: bubba's uses natural dormant bacteria that become active upon hitting that strong smelling cat pee, billions of enzymes destroy stains down to the carpet pad. competitors use active bacteria that die off and lose effect
  • Many uses: our enzyme based stain remover and cleaning solution can be used in all areas of your house, auto, kitchen, bathroom, laundry room and more. use to remove shoe odor, clean auto carpeting stains, use as clothes pretreat for removal of tough set in grass stains. litter box cleaner, or on furniture to remove odor causing bacteria
  • Carpet & rug institute certified: our pet pee cleaner and enzymatic odor remover is a top rated pet stain & odor miracle. don't be disappointed by other brands pet cleaner sprays. try bubbas pet enzyme treatment cleaner instead

4. Bubbas Super Strength Concentrate Pet Odor Eliminator Carpet Shampoo Solution | Odor

4
8.8/10 our score

  • Use in any national brand carpet shampooer- can be used in bissell, hoover, rug doctor or any cleaning machines. also use as area rug cleaner or upholstery cleaner for pet stains and odors
  • A simple solution for green carpet cleaning-all our pet cleaners are guaranteed-love it or your money back. proudly made in usa and used in hotels, indoor dog kennels and other commercial facilities.
  • Most carpet cleaners require the use of more carpet cleaning detergent. ours is very concentrated - economical. most carpet shampooing jobs will only use 1 to 3 oz of solution per room for cleaning.
  • Professional commercial grade cleaning solutions for home use- great as a cat urine odor remover, pet stain remover. removes cat odor, dog odor and eliminates tough urine smell stains in carpet
  • Top customer rated carpet shampoo cleaner-other odor and stain removers fail where we succeed. our carpet cleaner solution uses 1oz of detergent per gallon of water in any carpet cleaning machine

5. Professional Strength Stain & Odor Remover - Natural Enzyme Cleaner (Bulk 32oz)

5
8.6/10 our score

  • Natural citrus scent: entirely plant based and made from real ingredients, this pet stain and odor remover is not only effective, but also smells amazing. essential oils and natural enzymes create a lemongrass scent that will have you feeling like you've discovered natures miracle cleaning solution.
  • Satisfaction guarantee: at pawstruck, your satisfaction is our number one concern. that is why we stand behind our 30 day guarantee. if you are unsatisfied with any of our puppy supplies our customer support team wants to hear about it. with a variety of other products in the queue, we are confident we can find something to suit your needs.
  • Professional strength: this odor eliminator cleaner flat out works! use it on carpet, upholstery, hardwood, tile, and more to remove stains and smells from urine, vomit, blood, wine, waste, and many other messes. our enzyme formula is more effective than most harsh cleaning agents because it actually breaks down odor and stain causing residues rather than masking them.
  • Made in the usa with safe ingredients: this product is sourced and made in the united states. other brands often buy overseas leading to a less effective and potentially dangerous cleaner. adhering to the strictest us standards, you can rest assured our spray is more than just another carpet stain remover. our enzymatic formula is strong enough to remove set-in stains, ...
  • Natural, non-toxic & biodegradable: because this product is plant-based, it is entirely safe around both kids and pets. plant-based enzymes not only clean better than harsh cleaning agents, they also biodegrade quickly. additionally enzymes can help to both stop & even reverse pollution situations as they degrade, meaning you will actually help the environment by using it.

6. Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator | Urine Odor Remover

6
8.3/10 our score

  • 100% guaranteed-proudly made in the usa: if you're not 100% happy, we will refund it in full
  • child & pet safe: natural enzyme formula is the safest way to remove pet stains and odors.
  • scientifically formulated stain & odor eliminator: removes the stain and stink from your pets
  • Multi surface: use on carpet, wood, furniture, rugs, crates, upholstery, outdoor carpets etc.
  • enzyme powered: completely removes all pet stains and odors for urine, feces, vomit & drool.

7. ANGRY ORANGE 24 oz Ready-to-Use Citrus Pet Odor Eliminator Pet Spray - Urine

7
8.1/10 our score

  • Urine odor remover solution: our formula smells like fresh oranges because it is made from oranges!
  • Strong and safe: this pet spray has 2x more odor fighting power. safe to use around your pets and children
  • Fierce & fresh: all-natural & super-powerful cat and dog stain deodorizer
  • Ready to use: no more mixing! use this pet stain remover directly on dog pee, cat urine or solid waste
  • Multipurpose deodorizer: works on carpet, tile, wood floors, driveways, litter boxes, grass, pens, and more

8. Nature’s Miracle Stain and Odor Remover Dog, Odor Control Formula

8
7.8/10 our score

  • Safe for pets and home: when used and stored as directed, this formula can be used around your pets.
  • Fast-acting formula clings to surfaces to break down and remove embedded dirt and debris
  • Spot stain & odor remover: begins to break down and remove stains immediately on contact.
  • Trusted brand: from the maker of natures miracle products, the pet stain and odor removing brand you trust because it works!
  • Enzymatic formula: continues working as long as any bio-based mess is still present.
  • Light citrus scent: dog odor control formula gets your home smelling clean again.

9. BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain

9
7.5/10 our score

  • Satisfaction guaranteed: other pet odor enzyme sprays use active bacteria that are ineffective soon after you buy them. bubba's dormant bacteria formula is the best premium deep cleaning stain and pet urine enzyme carpet cleaner or your money back
  • Many uses: our enzyme based stain remover and cleaning solution can be used in all areas of your house, auto, kitchen, bathroom, laundry room and more. use to remove shoe odor, clean auto carpeting stains, use as clothes pretreat for removal of tough set in grass stains. litter box cleaner, or on furniture to remove odor causing bacteria
  • Best professional grade cleaning solution: scientifically formulated to be more potent than other pet odor enzyme cleaners for your flooring, upholstery, area rugs and carpets, yet safe to use around kids and pets. permanently destroys pet enzyme odors and stains
  • Pet stain and odor miracle: bubba's uses natural dormant bacteria that become active upon hitting that strong smelling cat pee, billions of enzymes destroy stains down to the carpet pad. competitors use active bacteria that die off and lose effect
  • Carpet & rug institute certified: our pet pee cleaner and enzymatic odor remover is a top rated pet stain & odor miracle. don't be disappointed by other brands pet cleaner sprays. try bubbas pet enzyme treatment cleaner instead

10. ANGRY ORANGE - Best Enzyme Pet Odor Eliminator and Stain Remover to Destroy

10
7.2/10 our score

  • Our new formula works overtime updated this year! use on carpets, floors, litter boxes, kennels, furniture, and all pet living areas.
  • Safe with a gentle scent safe to use around pets & children. fresh & gentle citrus scent really works furry freshness magic.
  • Destroys even the worst pet odors a nature's miracle, enzymatic powers deodorize and clean your worst urine, feces, or vomit stains.
  • Enzyme activated natural enzymatic bacteria activate instantly to fight stains on contact, destroying unwanted nastiness for up to 80hrs!
  • 100% satisfaction guaranteed angry orange cares about your happiness! if your not happy, well refund your order asap!

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