Best Pet Stain Remover Sprays In April 2025

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Check out our product review of the Best Pet Stain Remover Sprays. We tried 10 models and can tell you the absolute best varieties.

To help you in your search, we have completed this list of the Best Pet Stain Remover Sprays.

Top Rated Best Pet Stain Remover Sprays Of 2025

Rank	Product Name	Score
1	TriNova Natural Pet Stain and Odor Remover Eliminator - Advanced Enzyme Cleaner Spray Buy Now	9.7 Buy Now
2	OUT! Advanced Severe Stain & Odor Remover, 32 oz Buy Now	9.5 Buy Now
3	OUT! Orange Oxy Stain and Odor Remover | Pet Stain and Odor Remover Buy Now	9.1 Buy Now
4	Resolve Ultra Pet Stain & Odor Remover Spray, 32oz Buy Now	8.8 Buy Now
5	Resolve Urine Destroyer Spray Stain & Odor Remover, 32oz Buy Now	8.6 Buy Now
6	Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor Buy Now	8.3 Buy Now
7	Woolite INSTAclean Permanent Pet Stain Remover, 22oz (Pack of 2), 21809 Buy Now	8.1 Buy Now
8	Simple Solution Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Buy Now	7.8 Buy Now
9	Nature's Miracle Advanced Dog Stain & Odor Eliminator Spray, 32 oz Buy Now	7.5 Buy Now
10	Nature's Miracle Advanced Stain and Odor Eliminator Foam For Severe Cat Messes Aerosol Buy Now	7.2 Buy Now

1. TriNova Natural Pet Stain and Odor Remover Eliminator - Advanced Enzyme Cleaner Spray

• 100% natural cleaner - we are setting the "green standard' by using only natural and organic ingredients in our formula and listing everything right on the label.
• Safe around kids & pets - trinova understands your pets frequent the spaces where you and your children spend the most time as well. because of this, trinova's pet stain & odor remover contains a formula that leaves surfaces safe for your kids to keep on playing without any worry about harmful chemicals or toxins.
• Use it anywhere - use this natural pet stain remover on most surfaces such as bedding, mattress, cage, kennel, laundry, clothes, hardwood, litter box and more. even use it for small animals like hamsters, rat, and mice cages
• 100% satisfaction guarantee - we think you'll love our product, but if you don't just let us know and we'll refund your purchase price!
• Professional strength - trinova's pet stain & odor remover features a blend of natural enzymes that tackle stains and odors at their root to clean and neutralize. the enzymes work to break down the stains, drying out and disintegrating when they're finished to restore your carpet to like-new condition.

2. OUT! Advanced Severe Stain & Odor Remover, 32 oz

• No more ew old or new - effective on old and new problem areas.
• Cleaning awesomesauce - our 3x-concentrated pro-bacteria and enzyme formula removes the toughest pet stain and odor, such as urine, vomit, feces, blood and more.
• No hazmat suit required - no harsh chemicals our nature-inspired formula is safe to use around pets and children, when used as directed.
• Discourage repeat spritzes - prevents repeat marketing. helps remove the pheromones that draw your pet in for continual bathroom visits to the same spot.
• Clear the air - why cover up nasty odors when you can quickly neutralize them with out advanced severe stain and odor remover?

3. OUT! Orange Oxy Stain and Odor Remover | Pet Stain and Odor Remover

• Discourage repeat spritzes - prevents repeat marketing. helps remove the pheromones that draw your pet in for continual bathroom visits to the same spot.
• Come at me, stains - the toughest messes dont stand a chance. your days are numbered, urine, vomit, feces, and blood.
• No hazmat suit required - our oxy formula is safe to use around pets when used as directed
• Unleash the awesome power - out! orange oxy stain and odor remover delivers a wallop to tough stains and odors with our powerful oxidizing formula.

4. Resolve Ultra Pet Stain & Odor Remover Spray, 32oz

• Eliminates pet odors with odor stop technology
• Removes tough pet stains like urine, vomit, and feces from rugs and carpets also works great on everyday stains like red wine, grape juice, and greasy food
• Discourages pet resoiling
• Freshens with a light, clean scent

5. Resolve Urine Destroyer Spray Stain & Odor Remover, 32oz

• Helps prevent remarking
• Safe for pets when used as directed
• Neutralizes urine odors on contact
• Great for pet and people accidents
• Safe for carpets, fabrics, and hard floors

6. Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor

• Enzyme activated the key is getting to the problem deep-down. this spray contains natural enzymatic bacteria that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated.
• Certified gentle and safe chlorine free and color safe. safe to use around pets and children. no hazardous propellants, no residue left behind. so gentle its been certified safe for all carpets, earning the seal of approval by the trusted carpet and rug institute (cri)
• Every surface, every time for use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas -- anywhere stains happen.
• Eliminates stains, odors and residue if its gross, its gone. not just the stain, but the stink. from stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all.
• 100% satisfaction guaranteed an amazon best seller for a reason. if your stains and odors arent gone, neither is your money. well refund it in full

7. Woolite INSTAclean Permanent Pet Stain Remover, 22oz (Pack of 2), 21809

• Included components: 2 pack of formula
• 2 pack of pet stain remover. permanent stain removal in 30 seconds
• Safe for kids and pets when used as directed
• Oxy stain destroyer formula starts working on contact to mobilize, lift, and penetrate the stain at the source to remove stains in 30 seconds
• Instantly and permanently removes tough stains like urine, feces, vomit, tracked-in dirt, mud, blood
• Eliminates tough pet odors and discourages pets from resoiling

8. Simple Solution Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X

• Professional strength formula - extreme stain and odor remover is a professional strength pro-bacteria and enzyme formula that breaks down and eliminates stains and odors.
• New patented multi-functional sprayer - now designed with a new patented 3-in-1 nozle sprayer (foam, mist, and stream).
• Specifically for pet odors and organic stains - safely and quickly removes dog and cat urine, feces, and vomit on carpet, upholstery, bedding, fabric toys, clothing, or other water-safe surfaces in your home
• Designed for the toughest odors and organic stains- simple solution pet extreme stain and odor remover is three times stonger than our regular formula to eliminate tough dog and cat odors and stains.

9. Nature's Miracle Advanced Dog Stain & Odor Eliminator Spray, 32 oz

• Enzymatic formula: continues working as long as any bio-based mess is still present.
• Safe for pets and home: when used and stored as directed, this formula can be used around your pets.
• Trusted brand: from the maker of natures miracle products, the pet stain and odor removing brand you trust because it works!
• For severe dog messes: powerful enzymatic formula works to eliminate tough stains and odors from dog urine, diarrhea, vomit and other bio-based accidents.
• Discourages resoiling: removes the odor from even the toughest dog messes.
• Light fresh scent: dog odor control formula gets your home smelling clean again.

10. Nature's Miracle Advanced Stain and Odor Eliminator Foam For Severe Cat Messes Aerosol

• Foam penetrates down into carpet to power out severe cat messes
• Safe for use around pets and home when used as directed
• Works to eliminate the toughest pet odors
• Guaranteed to work or your money back