Best Urine Cleaner In July 2025

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To help you choose the Best Urine Cleaner, we’ve put together this comprehensive guide. We have tried to cover as much variety as possible. Hope you will find it helpful!

To help you in your search, we have completed this list of the Best Urine Cleaner.

Top Rated Best Urine Cleaner Of 2025

Rank Product Name Score
1
Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor
Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor
9.7
2
ANGRY ORANGE 24 oz Ready-to-Use Citrus Pet Odor Eliminator Pet Spray - Urine
ANGRY ORANGE 24 oz Ready-to-Use Citrus Pet Odor Eliminator Pet Spray - Urine
9.5
3
Angry Orange Pet Odor Eliminator for Dog and Cat Urine, Makes 1 Gallon
Angry Orange Pet Odor Eliminator for Dog and Cat Urine, Makes 1 Gallon
9.1
4
Bissell Professional Pet Urine Eliminator + Oxy Carpet Cleaning Formula, 48 oz, 1990
Bissell Professional Pet Urine Eliminator + Oxy Carpet Cleaning Formula, 48 oz, 1990
8.8
5
Simple Green Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine
Simple Green Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine
8.6
6
Nature’s Miracle P-97004 Urine Destroyer Dog, For Tough Urine Messes,Accushot 170 Oz
Nature’s Miracle P-97004 Urine Destroyer Dog, For Tough Urine Messes,Accushot 170 Oz
8.3
7
Nilodor Bio-Enzymatic Urine Digester with Odor Neutralizer, Original Fragrance -1 Gallon (128 ZYM)
Nilodor Bio-Enzymatic Urine Digester with Odor Neutralizer, Original Fragrance -1 Gallon (128 ZYM)
8.1

1. Rocco & Roxie Supply Professional Strength Stain and Odor Eliminator, Enzyme-Powered Pet Odor

1
9.7/10 our score

  • 100% satisfaction guaranteed an amazon best seller for a reason. if your stains and odors arent gone, neither is your money. well refund it in full
  • Certified gentle and safe chlorine free and color safe. safe to use around pets and children. no hazardous propellants, no residue left behind. so gentle its been certified safe for all carpets, earning the seal of approval by the trusted carpet and rug institute (cri)
  • Enzyme activated the key is getting to the problem deep-down. this spray contains natural enzymatic bacteria that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated.
  • Every surface, every time for use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas -- anywhere stains happen.
  • Eliminates stains, odors and residue if its gross, its gone. not just the stain, but the stink. from stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all.

2. ANGRY ORANGE 24 oz Ready-to-Use Citrus Pet Odor Eliminator Pet Spray - Urine

2
9.5/10 our score

  • Ready to use: no more mixing! use this pet stain remover directly on dog pee, cat urine or solid waste
  • Urine odor remover solution: our formula smells like fresh oranges because it is made from oranges!
  • Multipurpose deodorizer: works on carpet, tile, wood floors, driveways, litter boxes, grass, pens, and more
  • Strong and safe: this pet spray has 2x more odor fighting power. safe to use around your pets and children
  • Fierce & fresh: all-natural & super-powerful cat and dog stain deodorizer

3. Angry Orange Pet Odor Eliminator for Dog and Cat Urine, Makes 1 Gallon

3
9.1/10 our score

  • Makes (4) 32 ounce spray bottles: 1 gallon of pet odor remover and carpet cleaner solution from our 8 ounce bottle
  • Get rid of the toughest pet odors: angry orange is a commercial grade citrus pet odor remover
  • Multiple uses: angry orange odor eliminator for home can be used on carpets and tile, combats cat odor in litter boxes, removes pet odor in the yard and kennel surfaces, ammonia and methane odors, and anywhere else pet odor waste is a problem
  • Customer satisfaction: if you ever have an issue with this item we will send you a replacement on us, no questions asked
  • Safe and non toxic: angry orange pet urine odor remover is derived from the oil found in orange peels, biodegradable and non-toxic

4. Bissell Professional Pet Urine Eliminator + Oxy Carpet Cleaning Formula, 48 oz, 1990

4
8.8/10 our score

  • Permanently removes stains and odors at the source with the power of oxy
  • Cleans and protects from future stains with scotch gard protector
  • For use in bissell, hoover, and rug doctor upright deep cleaning machines
  • Discourages pets from urinating in the same spot again
  • Every bissell purchase helps save pets. bissell proudly supports bissell pet foundation and its mission to help save homeless pets.
  • Bissell's best formula for pet odors and stains, even tackles skunk odor

5. Simple Green Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine

5
8.6/10 our score

  • Use on carpets, rugs, pet bedding, upholstery, clothing, curtains, auto upholstery, litter boxes, crates and carriers, tile, finished wood, laminates, concrete and more
  • Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
  • Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
  • Non-toxic formula is safer for use around pets
  • Eliminates new, old and set-in stains

6. Nature’s Miracle P-97004 Urine Destroyer Dog, For Tough Urine Messes,Accushot 170 Oz

6
8.3/10 our score

  • Enzymatic formula: continues working as long as any bio-based mess is still present.
  • Light fresh scent: dog odor control formula gets your home smelling clean again.
  • For dog urine messes: powerful enzymatic formula is tough on dog urine and the yellow, sticky residue.
  • Safe for pets and home: when used and stored as directed, this formula can be used around your pets.
  • Trusted brand: from the maker of natures miracle products, the pet stain and odor removing brand you trust because it works!

7. Nilodor Bio-Enzymatic Urine Digester with Odor Neutralizer, Original Fragrance -1 Gallon (128 ZYM)

7
8.1/10 our score

  • Bio-enzymatic with an odor neutralizer that works around the clock
  • Mop or spray around urinals and commodes
  • Digests and eliminates odors at the source
  • Original fragrance is approved by the carpet and rug institute
  • Can be used on hard surface or carpeting

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